im·​mu·​no·​de·​fi·​cien·​cy | \ ˌi-myə-nō-di-ˈfi-shən(t)-sē How to pronounce immunodeficiency (audio) , i-ˌmyü-nō- \

Definition of immunodeficiency

: inability to produce a normal complement of antibodies or immunologically sensitized T cells especially in response to specific antigens

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Other Words from immunodeficiency

immunodeficient \ ˌi-​myə-​nō-​di-​ˈfi-​shənt How to pronounce immunodeficient (audio) , i-​ˌmyü-​nō-​ \ adjective

Examples of immunodeficiency in a Sentence

Recent Examples on the Web In addition to diagnosing and managing allergies, these specialists may also help manage asthma, certain lung conditions, and immunodeficiency disorders. Zee Krstic, Good Housekeeping, "25 Types of Doctors and What They Do for Patients' Health," 15 Sep. 2020 In Muskogee, Oklahoma, Madison Shoemaker, 22, and her mother care for her 7-year-old niece, who was diagnosed in early March with primary immunodeficiency disorder and must avoid public spaces. Kristen V Brown,, "In or Out of the Classroom, Back to School Could Be Dangerous for Some," 29 Aug. 2020 The Spanish teacher at Lookout Valley Middle and High School has asthma, while her daughter Emaline, 15, has asthma and an immunodeficiency. Marco Della Cava, USA TODAY, "Online school? In-person? How parents are making their own fall 2020 decisions as COVID-19 squabbles continue," 14 July 2020 Because the virus can still replicate, certain people (particularly those with immunodeficiencies) may have severe reactions. Beth Mole, Ars Technica, "The Ars COVID-19 vaccine primer: 100-plus in the works, 8 in clinical trials," 1 May 2020 Several of the children have rare genetic diseases including sickle cell anemia, giant axonal neuropathy and various other immunodeficiency diseases, according to the hospital spokeswoman. Joan Muwahed, ABC News, "Melania Trump lends a hand to ill children, helping to craft special valentines," 14 Feb. 2020 Today it is also prescribed for secondary immunodeficiency, which can occur when the body's immune system is compromised by viruses or treatments for cancer, although there may be other medicines for reinvigorating the immune system in those cases. Julie Appleby,, "As off-label use spreads for lifesaving niche drugs, supplies grow scarce, leaving patients in the lurch," 27 Sep. 2019 Valid medical reasons include when a child is undergoing chemotherapy, has a gelatin allergy or suffers from a severe immunodeficiency disorder, Governing magazine reports. NBC News, "Jessica Biel denies she's anti-vaccination after lobbying against California bill," 13 June 2019 People who are sick, suffer from immunodeficiency disorders or those with open wounds should not go into the river. Taryn Luna, sacbee, "E. coli levels drop at popular Sacramento beach | The Sacramento Bee," 21 Apr. 2018

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'immunodeficiency.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of immunodeficiency

1969, in the meaning defined above

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Time Traveler for immunodeficiency

Time Traveler

The first known use of immunodeficiency was in 1969

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Statistics for immunodeficiency

Last Updated

21 Sep 2020

Cite this Entry

“Immunodeficiency.” Dictionary, Merriam-Webster, Accessed 29 Oct. 2020.

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More Definitions for immunodeficiency


How to pronounce immunodeficiency (audio)

English Language Learners Definition of immunodeficiency

medical : a condition in which your body cannot produce enough of the substances or cells that it would normally produce to fight infection


im·​mu·​no·​de·​fi·​cien·​cy | \ -di-ˈfish-ən-sē How to pronounce immunodeficiency (audio) \
plural immunodeficiencies

Medical Definition of immunodeficiency

: inability to produce a normal complement of antibodies or immunologically sensitized T cells especially in response to specific antigens — see aids

Other Words from immunodeficiency

immunodeficient \ -​ənt How to pronounce immunodeficient (audio) \ adjective

More from Merriam-Webster on immunodeficiency

Nglish: Translation of immunodeficiency for Spanish Speakers

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