hyperstimulation

noun

hy·​per·​stim·​u·​la·​tion ˌhī-pər-ˌstim-yə-ˈlā-shən 

variants or hyper-stimulation

: excessive or extreme stimulation : the act or process of excessively stimulating something or someone

The donors were fertile women who underwent controlled ovarian hyperstimulation and … ultrasound-directed aspiration of oocytes for the sole purpose of donation.

—Mark V. Sauer et al.

hyperstimulate

ˌhī-pər-ˈstim-yə-ˌlāt 

transitive verb

or hyper-stimulate

hyperstimulated or hyper-stimulated; hyperstimulating or hyper-stimulating

… the estrogen does indeed hyperstimulate the ovaries, sometimes causing the egg follicles to enlarge to almost cyst-like proportions.

—Natalie Angier

hyperstimulating adjective

or hyper-stimulating

Several grown-ups said their children were at first overwhelmed by the party's hyperstimulating environment.

—Cynthia Rupe

Examples of hyperstimulation in a Sentence

Recent Examples on the Web

Baylis, at Dalhousie University, and others worry about risks that may not yet be apparent, to the babies themselves, the women having the babies and the women donating the eggs, such as a dangerous hyperstimulation of their ovaries. —Rob Stein, NPR, 16 July 2025

Some people experience ovarian hyperstimulation, which can lead in rare cases to hospitalization. —Kristen V. Brown, The Atlantic, 27 Jan. 2025

Women who donate their eggs for the pregnancy face the rare risk of potentially fatal hyperstimulation syndrome, and the long-term consequences of the fertility drugs are unknown. —Lili Rutai, The Dial, 7 Jan. 2025

Additionally, the required hormone injections can cause ovarian hyperstimulation syndrome, where the ovaries become swollen and painful. —New Atlas, 17 Dec. 2024

The high doses of hormones often result in side effects like bloating, nausea and vomiting and even ovarian hyperstimulation syndrome, Radenkovic says. —Alexandra York, Forbes, 16 Dec. 2024

Beyond these concerns, the biggest thing egg donors — like IVF and egg-freezing patients — have to watch out for is a condition called ovarian hyperstimulation syndrome, which causes fluid retention in the abdomen. —Anna North, Vox, 7 Dec. 2018

Word History

First Known Use

1834, in the meaning defined above

Rhymes for hyperstimulation

• acclimatisation
• acclimatization
• acidification
• actualization
• annualization
• autocorrelation
• autoregulation
• beatification
• beneficiation
• biodegradation
• biotransformation
• bureaucratization

Medical Definition

hyperstimulation

noun

hy·​per·​stim·​u·​la·​tion -ˌstim-yə-ˈlā-shən 

: excessive or increased stimulation

The donors were fertile women who underwent controlled ovarian hyperstimulation …

—Mark V. Sauer et al., The New England Journal of Medicine

hyperstimulate

-ˈstim-yə-ˌlāt 

verb

hyperstimulated; hyperstimulating

… the estrogen does indeed hyperstimulate the ovaries, sometimes causing the egg follicles to enlarge to almost cyst-like proportions.

—Natalie Angier, The New York Times