hy·​droxy·​zine | \ hī-ˈdräk-sə-ˌzēn How to pronounce hydroxyzine (audio) \

Definition of hydroxyzine

: a compound C21H27ClN2O2 used as an antihistamine and tranquilizer

Examples of hydroxyzine in a Sentence

Recent Examples on the Web Smith-Fields’ autopsy results indicated that her cause of death was a combination of fentanyl, promethazine, hydroxyzine, and alcohol. Jenna Caldwell, Time, 17 Feb. 2022 In her purse, police found several medications, including tramadol, suspected Ambien, vitamin E, butalbital-acetaminophen-caffeine, ferrous sulfate, hydroxyzine hydrochloride and nadolol. Bob Sandrick, cleveland, 27 Dec. 2019 Tests by the Office of the Chief Medical Examiner showed Dustin died of acute intoxication from the combined effects of fentanyl, hydroxyzine and a compound used to make fentanyl called 4-ANPP. Jesse Leavenworth, courant.com, 19 Nov. 2019 An autopsy revealed the victim died from an overdose of hydroxyzine, fentanyl and morphine, the affidavit said. Nicholas Rondinone, courant.com, 24 May 2017

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'hydroxyzine.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

First Known Use of hydroxyzine

1956, in the meaning defined above

History and Etymology for hydroxyzine

hydroxy- + piperazine

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Time Traveler for hydroxyzine

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The first known use of hydroxyzine was in 1956

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Cite this Entry

“Hydroxyzine.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/hydroxyzine. Accessed 28 May. 2022.

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More Definitions for hydroxyzine


hy·​droxy·​zine | \ hī-ˈdräk-sə-ˌzēn How to pronounce hydroxyzine (audio) \

Medical Definition of hydroxyzine

: a compound that is administered usually in the form of its dihydrochloride C21H27ClN2O2·2HCl or pamoate C21H27ClN2O2·C23H16O6 and is used as an antihistamine and tranquilizer — see vistaril


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