histocompatibility

noun

his·​to·​com·​pat·​i·​bil·​i·​ty ˈhi-(ˌ)stō-kəm-ˌpa-tə-ˈbi-lə-tē How to pronounce histocompatibility (audio)
: a state of mutual tolerance that allows some tissues to be grafted effectively to others compare major histocompatibility complex

Examples of histocompatibility in a Sentence

Recent Examples on the Web
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Scientists also mapped a region on chromosome 6 most genetically tied to Type 1 diabetes called the major histocompatibility complex, or MHC, with data from 29,000 people. Noah Lyons, San Diego Union-Tribune, 8 May 2026 Research into the major histocompatibility complex (MHC), a cluster of genes central to immune function, has established that humans are unconsciously drawn to partners whose MHC profile differs from their own. Scott Travers, Forbes.com, 6 May 2026 The analysis reveals an over-representation of the domestic cat's genes that are linked to immune function, such as the major histocompatibility complex, in the European wildcat's genome. Scott Travers, Forbes, 15 Feb. 2024 Our personal smells are tied to the major histocompatibility complex (MHC) that governs our immune system, says Pamela Dalton, a cognitive psychologist at Monell Chemical Senses Center. Sophia Solano, Washington Post, 14 June 2023 The transplant system and all of its interdependent components — donor families, donor hospitals, organ procurement organizations, transplant programs, histocompatibility laboratories, and others — must work together to equitably care for all patients waiting for organs. Richard N. Formica, STAT, 24 Apr. 2022

Word History

First Known Use

1948, in the meaning defined above

Time Traveler
The first known use of histocompatibility was in 1948

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Cite this Entry

“Histocompatibility.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/histocompatibility. Accessed 12 May. 2026.

Medical Definition

histocompatibility

noun
his·​to·​com·​pat·​i·​bil·​i·​ty ˈhis-(ˌ)tō-kəm-ˌpat-ə-ˈbil-ət-ē How to pronounce histocompatibility (audio)
plural histocompatibilities
often attributive
: a state of mutual tolerance between tissues that allows them to be grafted effectively see major histocompatibility complex
histocompatible adjective
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