histamine
noun
his·ta·mine
ˈhi-stə-ˌmēn 
-mən
-mən
: a compound C5H9N3 especially of mammalian tissues that causes dilation of capillaries, contraction of smooth muscle, and stimulation of gastric acid secretion, that is released during allergic reactions, and that is formed by decarboxylation of histidine
Examples of histamine in a Sentence
Recent Examples on the Web
Duah points out that while estrogen and histamine are connected, histamine isn’t considered a primary driver of perimenopause—research points to neurotransmitter activity as the main culprit behind brain fog, sleep disturbances and hot flashes.
—
Helen Carefoot, Flow Space, 29 May 2026
Antihistamine eye drops help block the release of histamines, a substance that the body releases after exposure to allergens.
—Neelam Patadia, The Conversation, 27 May 2026
Goodson says that individuals with histamine intolerance may experience symptoms like headaches or digestive discomfort when consuming fermented foods, as these products can be naturally high in histamines.
—Daryl Austin, USA Today, 23 May 2026
But right now, most experts don’t think that histamines have a direct impact on the root cause of perimenopause or menopause symptoms.
—Kara Smythe, EverydayHealth.com, 15 May 2026
See All Example Sentences for histamine
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Helen Carefoot, Flow Space, 29 May 2026
Antihistamine eye drops help block the release of histamines, a substance that the body releases after exposure to allergens.
—Neelam Patadia, The Conversation, 27 May 2026
Goodson says that individuals with histamine intolerance may experience symptoms like headaches or digestive discomfort when consuming fermented foods, as these products can be naturally high in histamines.
—Daryl Austin, USA Today, 23 May 2026
But right now, most experts don’t think that histamines have a direct impact on the root cause of perimenopause or menopause symptoms.
—Kara Smythe, EverydayHealth.com, 15 May 2026
See All Example Sentences for histamine
Cite this Entry
“Histamine.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/histamine. Accessed 3 Jun. 2026.
Copy CitationKids Definition
histamine
noun
his·ta·mine
ˈhis-tə-ˌmēn
-mən
: a compound that occurs in many animal tissues and plays an important part in allergic reactions (as in hives, asthma, and hay fever)
Medical Definition
histamine
noun
his·ta·mine
ˈhis-tə-ˌmēn
-mən
-mən
: a compound C5H9N3 especially of mammalian tissues that causes dilatation of capillaries, contraction of smooth muscle, and stimulation of gastric acid secretion, that is released during allergic reactions, and that is formed by decarboxylation of histidine
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