Definition of histamine
: a compound C5H9N3 especially of mammalian tissues that causes dilation of capillaries, contraction of smooth muscle, and stimulation of gastric acid secretion, that is released during allergic reactions, and that is formed by decarboxylation of histidine
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Merriam-Webster unabridged
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Time Traveler for histamine
The first known use of histamine was circa 1913
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