heterozygote

noun

het·​ero·​zy·​gote ˌhe-tə-rō-ˈzī-ˌgōt How to pronounce heterozygote (audio)
: a heterozygous individual

Examples of heterozygote in a Sentence

Recent Examples on the Web
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Though by definition these loss-of-function variants don't kill you, in general there is the assumption that this class of mutants does exhibit some fitness drag (e.g., the fitness of a heterozygote for a variant which is lethal as a homozygote genotype may be ~0.90). Razib Khan, Discover Magazine, 22 Feb. 2012

Word History

First Known Use

1902, in the meaning defined above

Time Traveler
The first known use of heterozygote was in 1902

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Cite this Entry

“Heterozygote.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/heterozygote. Accessed 10 Sep. 2025.

Kids Definition

heterozygote

noun
het·​ero·​zy·​gote ˌhet-ə-rō-ˈzī-ˌgōt How to pronounce heterozygote (audio)
: a heterozygous individual

Medical Definition

heterozygote

noun
het·​ero·​zy·​gote -ˈzī-ˌgōt How to pronounce heterozygote (audio)
: a heterozygous individual
heterozygotic adjective

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