hepatotoxicity

noun

hep·​a·​to·​tox·​ic·​i·​ty ˌhe-pə-tō-täk-ˈsi-sə-tē How to pronounce hepatotoxicity (audio)
hi-ˌpa-tə-
1
: a state of toxic damage to the liver
2
: a tendency or capacity to cause hepatotoxicity

Examples of hepatotoxicity in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
How many fatalities need to occur in AAV gene therapy when growing consensus is pointing to sirolimus to prevent liver hepatotoxicity? Kat Bryant Knudson, STAT, 31 July 2026 After eating a meal with the mushrooms, the individuals suffered from acute hepatotoxicity due to severe mushroom poisoning. Sabrina Weiss, PEOPLE, 4 Dec. 2025

Word History

First Known Use

1952, in the meaning defined at sense 1

Time Traveler
The first known use of hepatotoxicity was in 1952

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Cite this Entry

“Hepatotoxicity.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/hepatotoxicity. Accessed 8 Aug. 2026.

Medical Definition

hepatotoxicity

noun
he·​pa·​to·​tox·​ic·​i·​ty -täk-ˈsis-ət-ē How to pronounce hepatotoxicity (audio)
plural hepatotoxicities
1
: a state of toxic damage to the liver
2
: a tendency or capacity to cause hepatotoxicity
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