guanine

noun
gua·​nine | \ ˈgwä-ˌnēn How to pronounce guanine (audio) \

Definition of guanine

: a purine base C5H5N5O that codes genetic information in the polynucleotide chain of DNA or RNA — compare adenine, cytosine, thymine, uracil

Examples of guanine in a Sentence

Recent Examples on the Web These differences - the base adenine in one position instead of guanine - determine everything from harmless diversity (brown hair vs. blond) to the defects that cause disease. Mark Johnson And Kathleen Gallagher, Milwaukee Journal Sentinel, "One in a billion: Researchers seek clues in Nicholas' DNA -- and find more than they expected.," 21 Dec. 2010 On the X chromosome, on the gene XIAP, the rest of humanity has the sequence thymine-guanine-thymine. Mark Johnson And Kathleen Gallagher, Milwaukee Journal Sentinel, "One in a billion: Researchers seek clues in Nicholas' DNA -- and find more than they expected.," 21 Dec. 2010 The four bases of virus RNA are written in an alphabet composed of nucleotide chemicals: adenine (A), cytosine (C), guanine (G) and uracil (U). Robert Lee Hotz, WSJ, "‘Really Diabolical’: Inside the Coronavirus That Outsmarted Science," 7 Sep. 2020 Instead of hooks and loops, the Velcro has the nucleotides that make up DNA: adenine, cytosine, guanine and thymine. Gaia Squarci, Smithsonian Magazine, "The Virus Hunters," 10 Aug. 2020 One serves as a template, laying down sequences of the four bases that make up DNA molecules: adenine (A), thymine (T), guanine (G) and cytosine (C). Lydia Denworth, Scientific American, "A Breakthrough in Genetic Medicine for Rare Diseases," 3 Mar. 2020 Part of this gene contains repeated segments for three of the letters of the DNA code—cytosine, adenine and guanine, which are known as CAG repeats. Bret Stetka, Scientific American, "Antisense Drugs for Huntington’s, ALS and Prion Diseases Could Meet the Dire Need for Brain Treatments," 15 Aug. 2019 However, rather than the conventional duo of base pairs, adenine and uracil or cytosine and guanine, the molecules form hexamers, or six-membered rings. Quanta Magazine, "Chemists Seek Possible Precursor to RNA," 5 Feb. 2014 In 1953, scientists proposed that DNA is structured as a double helix, with the chemical bases—adenine (A), cytosine (C), guanine (G), and thymine (T)—stacked up in pairs between two intertwining lengths of sugar and phosphate. Ryan Rossotto, National Geographic, "DNA, explained," 12 June 2019

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'guanine.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

See More

First Known Use of guanine

1850, in the meaning defined above

History and Etymology for guanine

guano + -ine; from its being found especially in guano

Keep scrolling for more

Learn More about guanine

Time Traveler for guanine

Time Traveler

The first known use of guanine was in 1850

See more words from the same year

Statistics for guanine

Last Updated

7 Nov 2020

Cite this Entry

“Guanine.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/guanine. Accessed 25 Nov. 2020.

Keep scrolling for more

More Definitions for guanine

guanine

noun
gua·​nine | \ ˈgwän-ˌēn How to pronounce guanine (audio) \

Medical Definition of guanine

: a purine base C5H5N5O that codes genetic information in the polynucleotide chain of DNA or RNA — compare adenine, cytosine, thymine, uracil

More from Merriam-Webster on guanine

Britannica.com: Encyclopedia article about guanine

Comments on guanine

What made you want to look up guanine? Please tell us where you read or heard it (including the quote, if possible).

WORD OF THE DAY

Test Your Vocabulary

A Thanksgiving Word Quiz

  • a traditional thanksgiving dinner
  • November comes from a word for which of the following numbers?
Spell It

Can you spell these 10 commonly misspelled words?

TAKE THE QUIZ
Citation

Test Your Knowledge - and learn some interesting things along the way.

TAKE THE QUIZ
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!