: any of a breed of tall massive powerful smooth-coated dogs
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The series, which introduced supernatural mystery-solving teens Fred Jones, Daphne Blake, Velma Dinkley, and Shaggy Rogers and their talking Great Dane Scooby-Doo, originally aired on CBS from 1969-76.—Denise Petski, Deadline, 10 June 2026 Nunez offers a beautifully insightful and moving account of a solitary writer in Manhattan who inherits a massive Great Dane from her friend who has died by suicide.—Literary Hub, 9 June 2026 The arrangement appeared to be working out well until that morning, when less than an hour after Loyalty's arrival, Miller called 911 to report that the boy had been mauled by her two Great Dane/Mastiff mixes.—Chris Spargo, PEOPLE, 27 Apr. 2026 The Great Dane puppy at the center of the mystery is, of course, Scooby-Doo himself.—Hanna Wickes, Charlotte Observer, 24 Feb. 2026 See All Example Sentences for Great Dane