gray matter

noun

1

: neural tissue especially of the brain and spinal cord that contains nerve-cell bodies as well as nerve fibers and has a brownish-gray color

2

: brains, intellect

Synonyms

• brain(s)
• brainpower
• headpiece
• intellect
• intellectuality
• intelligence
• mentality
• reason
• sense
• smarts

Examples of gray matter in a Sentence

she's got the gray matter to figure that equation out

Recent Examples on the Web

While gray matter naturally decreases with age, research indicates that adults who engage in excessive screen time have significantly lower gray matter volume compared to their peers. —Caroline Castrillon, Forbes.com, 18 June 2025

Their temporary electronic face tattoo, or e-tattoo, can read brain waves and not only detect when the ol' gray matter is overworked, but also predict when exhaustion is approaching. —Paul McClure 29, New Atlas, 29 May 2025

Prior research has indicated caffeine consumption may be associated with acute reductions in gray matter volume. —New Atlas, 11 Feb. 2025

One particular question the researchers wanted to answer was whether the influence of caffeine on gray matter was a result of the drug’s effect on sleep, as it has been shown that sleep deprivation or disruption can lead to acute reductions in gray matter. —New Atlas, 11 Feb. 2025

Word History

First Known Use

1809, in the meaning defined at sense 1

Rhymes for gray matter

• backscatter
• antimatter
• atter
• batter
• blatter
• catarrh
• chatter
• clatter
• fatter
• flatter
• hatter
• latter

Kids Definition

gray matter

noun

1

: nerve tissue especially of the brain and spinal cord that has a brownish gray color

2

: intelligence sense 1

Medical Definition

gray matter

noun

: neural tissue especially of the brain and spinal cord that contains cell bodies as well as nerve fibers, has a brownish gray color, and forms most of the cortex and nuclei of the brain, the columns of the spinal cord, and the bodies of ganglia

called also gray substance