glob·​ule ˈglä-(ˌ)byül How to pronounce globule (audio)
: a tiny globe or ball especially of a liquid
globules of mercury

Example Sentences

fat globules of hot wax dripping onto the table
Recent Examples on the Web Diagram of the phosopholipid layer surrounding a fat globule [3]. Vince C Reyes, Discover Magazine, 28 May 2013 The fractal globule makes perfect sense as the shape of a genome. Ed Yong, Discover Magazine, 29 Dec. 2011 Formula traditionally has lacked these milk fat globule membranes, but researchers and companies are testing bovine versions in infant formula. Alice Callahan, Discover Magazine, 18 Oct. 2019 Through their research over the past few years, Aiden and his colleagues have discovered that at the level of a megabase—1 million base pairs—the human genome has wrapped itself into a structure known as a fractal globule. Katherine Harmon, Scientific American, 2 Dec. 2011 There’s also some promising research about the benefits of a compound called the milk-fat globule membrane, which is intact in cheese but not in milk or butter. Gilad Edelman, Wired, 22 Feb. 2021 After mixing alcohol and aloe vera gel in a bowl, the mix created weird globules, and the gel began to separate and sink to the bottom. New York Times, 3 Apr. 2020 While compelling evidence on the benefits of additives like prebiotics and probiotics is lacking, one exception is milk fat globule membrane (MFGM), a protein present in breastmilk that contains several important biologically active factors. Susan Reslewic Keatley, New York Times, 18 Apr. 2020 But after examining the globules with a host of new technologies, including DNA analysis and micro-sized arenas to observe the small, squishy blobs in three dimensions, the team revealed a more surprising origin. Cheryl Ames, National Geographic, 13 Feb. 2020 See More

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'globule.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History


French, from Latin globulus, diminutive of globus

First Known Use

1661, in the meaning defined above

Time Traveler
The first known use of globule was in 1661

Dictionary Entries Near globule

Cite this Entry

“Globule.” Dictionary, Merriam-Webster, Accessed 31 Mar. 2023.

Kids Definition


: a tiny globe or ball
globules of fat

Medical Definition


glob·​ule ˈgläb-(ˌ)yü(ə)l How to pronounce globule (audio)
: a small globular body or mass (as a drop of water or a bead of sweat)
globules of fat
specifically : a small spherical pill of compressed sugar usually saturated with an alcoholic tincture and used in homeopathy

More from Merriam-Webster on globule

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