general paresis

noun

: syphilis of the central nervous system that is characterized by memory loss, muscle weakness, progressive dementia, seizures, and paralysis

Word History

First Known Use

1862, in the meaning defined above

Time Traveler
The first known use of general paresis was in 1862

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Cite this Entry

“General paresis.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/general%20paresis. Accessed 3 Jul. 2026.

Medical Definition

general paresis

noun
: neurosyphilis that is marked by chronic inflammation of the brain and meninges and is characterized by memory loss, muscle weakness, personality changes, progressive dementia, seizures, and generalized paralysis

called also dementia paralytica

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