follicle

noun

fol·​li·​cle ˈfä-li-kəl How to pronounce follicle (audio)
1
a
: a small anatomical cavity or deep narrow-mouthed depression
b
: a small lymph node
c
: a vesicle in the mammalian ovary that contains a developing egg surrounded by a covering of cells
especially : graafian follicle
2
: a dry dehiscent one-celled many-seeded fruit (as of the milkweed) that has a single carpel and opens along one suture
follicular adjective

Examples of follicle in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
The longer a follicle sits in a petri dish, the lower its survival rate. Daniel Fusch, USA Today, 2 Jan. 2026 As daylight decreases, a larger group of follicles may enter the resting phase. Connie Etemadi, Miami Herald, 31 Dec. 2025 Used on dry hair before shampooing, the rinse-out treatment relies on lactic, tartaric, and benzoic acids to loosen dead skin, unclog follicles, and rebalance the scalp—key steps for managing dandruff and flakiness. Allure, 18 Dec. 2025 Its formula is primarily designed to combat chronic and acute stress on the scalp and follicles, inflammation, and oxidative damage. Gina Vaynshteyn, StyleCaster, 25 Nov. 2025 See All Example Sentences for follicle

Word History

Etymology

New Latin folliculus, from Latin, diminutive of follis bag — more at fool

First Known Use

1715, in the meaning defined at sense 1a

Time Traveler
The first known use of follicle was in 1715

Browse Nearby Words

Cite this Entry

“Follicle.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/follicle. Accessed 9 Jan. 2026.

Kids Definition

follicle

noun
fol·​li·​cle ˈfäl-i-kəl How to pronounce follicle (audio)
1
a
: a small cavity or a deep bodily depression with a narrow mouth (as one from which a hair grows)
2
: a dry one-celled fruit (as in the milkweed) that splits open by one seam when ripe
follicular adjective

Medical Definition

follicle

noun
fol·​li·​cle ˈfäl-i-kəl How to pronounce follicle (audio)
1
: a small anatomical cavity or deep narrow-mouthed depression
especially : a small simple or slightly branched gland : crypt
2
: a small lymph node
3
: a vesicle in the mammalian ovary that contains a developing egg surrounded by a covering of cells : ovarian follicle
especially : graafian follicle
follicular adjective

More from Merriam-Webster on follicle

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