follicle

noun

fol·​li·​cle ˈfä-li-kəl 

1

a

: a small anatomical cavity or deep narrow-mouthed depression

b

: a small lymph node

c

: a vesicle in the mammalian ovary that contains a developing egg surrounded by a covering of cells

especially : graafian follicle

2

: a dry dehiscent one-celled many-seeded fruit (as of the milkweed) that has a single carpel and opens along one suture

follicular

fə-ˈli-kyə-lər 

fä-

adjective

Examples of follicle in a Sentence

Recent Examples on the Web

But dermatologist Uchenne Okereke told Allure that when the follicles are still intact and only the ends look sparse, that’s a sign of breakage rather than true loss. — Ryan Brennan, Miami Herald, 14 Sep. 2026

That’s courtesy of the charcoal, which draws out follicle-clogging impurities that cause buildup on the scalp. — Brigitt Earley, Glamour, 14 Sep. 2026

Curved follicles, previous scarring, low density and extensive miniaturization require additional planning. — Malana Vantyler, Kansas City Star, 2 Sep. 2026

Hair-follicle tests showed the girl had methadone in her system, while the boy tested positive for methamphetamine and methadone. — Greg Wehner, FOXNews.com, 2 Sep. 2026

Word History

Etymology

New Latin folliculus, from Latin, diminutive of follis bag — more at fool

First Known Use

1715, in the meaning defined at sense 1a

Phrases Containing follicle

• follicle mite
• follicle-stimulating hormone
• graafian follicle
• hair follicle

Rhymes for follicle

• diabolical
• symbolical

Kids Definition

follicle

noun

fol·​li·​cle ˈfäl-i-kəl 

1

a

: a small cavity or a deep bodily depression with a narrow mouth (as one from which a hair grows)

b

: graafian follicle

2

: a dry one-celled fruit (as in the milkweed) that splits open by one seam when ripe

follicular

fə-ˈlik-yə-lər 

fä-

adjective

Medical Definition

follicle

noun

fol·​li·​cle ˈfäl-i-kəl 

1

: a small anatomical cavity or deep narrow-mouthed depression

especially : a small simple or slightly branched gland : crypt

2

: a small lymph node

3

: a vesicle in the mammalian ovary that contains a developing egg surrounded by a covering of cells : ovarian follicle

especially : graafian follicle

follicular

fə-ˈlik-yə-lər, fä- 

adjective