flu·​ox·​e·​tine flü-ˈäk-sə-ˌtēn How to pronounce fluoxetine (audio)
: an antidepressant drug C17H18F3NO that is administered in the form of its hydrochloride and enhances serotonin activity

Examples of fluoxetine in a Sentence

Recent Examples on the Web For instance, the doctor observed that at least one primate was being treated with fluoxetine—generic Prozac—for depression. Dhruv Mehrotra, WIRED, 13 Dec. 2023 There are also four medications (sertraline, paroxetine, fluoxetine, and venlafaxine) that have a conditional recommendation to treat PTSD. Laura Baisas, Popular Science, 30 Nov. 2023 To demonstrate the machine’s range, the MIT team produced four pharmaceuticals: diphenhydramine hydrochloride (Benadryl), diazepam (Valium), fluoxetine hydrochloride (Prozac), and the local anesthetic lidocaine hydrochloride. IEEE Spectrum, 31 Mar. 2016 If treatment without medication is unhelpful, or specific behavioral programs are not available, or the person prefers medication, then SSRI medicines, such as fluoxetine or citalopram, are often used. Dr. Keith Roach, oregonlive, 5 Sep. 2023 Unlike some other antidepressants, such as fluoxetine (marketed as Prozac), zuranolone doesn’t increase serotonin, a neurotransmitter that acts as a hormone and carries messages from the brain to regulate a range of bodily functions, including temperature, sleep, and hunger. Manasee Wagh, Popular Mechanics, 22 Aug. 2023 Psychedelics and trauma Why would one to two psychedelic therapy sessions be more effective than taking daily prescription medications like fluoxetine (Prozac) and paroxetine (Paxil)? Receiving a cancer diagnosis and experiencing adverse effects from treatments can be traumatic. C. Michael White, Fortune Well, 17 Apr. 2023 Medications like fluoxetine, paroxetine, and escitalopram have shown to delay ejaculation as a side-effect of the drugs, Dr. Kaufman said. Korin Miller, Health, 23 Mar. 2023 Drugs cost money, but not much: generic fluoxetine, i.e. non-brand-name Prozac, currently costs less than 10 cents per day. Neuroskeptic, Discover Magazine, 13 May 2010 See More

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'fluoxetine.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History


International Scientific Vocabulary, probably from fluor- + oxy + methyl + amine

First Known Use

1975, in the meaning defined above

Time Traveler
The first known use of fluoxetine was in 1975

Dictionary Entries Near fluoxetine

Cite this Entry

“Fluoxetine.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/fluoxetine. Accessed 26 Feb. 2024.

Medical Definition


flu·​ox·​e·​tine ˌflü-ˈäk-sə-ˌtēn How to pronounce fluoxetine (audio)
: a drug that functions as an SSRI and is administered in the form of its hydrochloride C17H18F3NO·HCl especially to treat depression, panic disorder, and obsessive-compulsive disorder see prozac

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