fentanyl

noun

fen·​ta·​nyl ˈfen-tə-ˌnil How to pronounce fentanyl (audio)
: a synthetic opioid narcotic analgesic C22H28N2O with pharmacological action similar to morphine that is administered transdermally as a skin patch and in the form of its citrate C22H28N2O·C6H8O7 is administered orally or parenterally (as by intravenous or epidural injection)

Examples of fentanyl in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Tucker, the Special Agent in Charge for Texas and Oklahoma, said visitors should leave with memories of Southern hospitality and brisket – not encounters with illicit drugs laced with a deadly dose of fentanyl. Marvin Hurst, CBS News, 20 June 2026 Another told The Times she was arrested while high on fentanyl and had to detox without medication while chained to a metal bar for hours. Gavin J. Quinton, Los Angeles Times, 19 June 2026 And in every instance, nitazenes were detected alongside fentanyl, and often with a cocktail of other drugs such as heroin, cocaine, methamphetamine, and benzodiazepines. Jonathan Moens — Bellingcat, STAT, 18 June 2026 Arce was sentenced to 60 months in prison in January after pleading guilty to conspiracy to distribute and to possess with intent to distribute 40 grams or more of fentanyl. Justin Muszynski, Hartford Courant, 17 June 2026 See All Example Sentences for fentanyl

Word History

Etymology

probably alteration of phenethyl, a monovalent radical derived from ethylbenzine, from phen- + ethyl

First Known Use

1964, in the meaning defined above

Time Traveler
The first known use of fentanyl was in 1964

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Cite this Entry

“Fentanyl.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/fentanyl. Accessed 28 Jun. 2026.

Medical Definition

fentanyl

noun
fen·​ta·​nyl ˈfent-ᵊn-ˌil How to pronounce fentanyl (audio)
: a synthetic opioid narcotic analgesic C22H28N2O with pharmacological action similar to morphine that is administered transdermally as a skin patch and in the form of its citrate C22H28N2O·C6H8O7 is administered orally or parenterally

Note: Fentanyl is marketed under the trademark Actiq.

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