fentanyl

noun

fen·​ta·​nyl ˈfen-tə-ˌnil How to pronounce fentanyl (audio)
nonstandard -ˌnȯl
: a synthetic opioid narcotic analgesic C22H28N2O with pharmacological action similar to morphine that is administered transdermally as a skin patch and in the form of its citrate C22H28N2O·C6H8O7 is administered orally or parenterally (as by intravenous or epidural injection)

Examples of fentanyl in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Jett died from an acute overdose of fentanyl and the manner of death was homicide, according to a toxicology report cited by Stephan. — Summer Lin, Los Angeles Times, 22 Oct. 2026 San Francisco police said cychlorphine, estimated to be 10 times estimated more powerful than fentanyl, can be found in counterfeit pills designed to look like Xanax, Adderall and Oxycontin. — Carlos E. Castañeda, CBS News, 21 Oct. 2026 Continue reading … -- IN OTHER NEWS HIGH POTENCY — ‘Super-drug’ 10 times stronger than fentanyl linked to deaths across multiple states. — FOXNews.com, 20 Oct. 2026 But knowing exactly how much fentanyl is present in a sample would be extremely helpful both for drug users and the healthcare workers treating them. — Prabhat Ranjan Mishra, Interesting Engineering, 17 Oct. 2026 See All Example Sentences for fentanyl

Word History

Etymology

probably alteration of phenethyl, a monovalent radical derived from ethylbenzine, from phen- + ethyl

First Known Use

1964, in the meaning defined above

Time Traveler
The first known use of fentanyl was in 1964

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Cite this Entry

“Fentanyl.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/fentanyl. Accessed 25 Oct. 2026.

Medical Definition

: a synthetic opioid narcotic analgesic C22H28N2O with pharmacological action similar to morphine that is administered transdermally as a skin patch and in the form of its citrate C22H28N2O·C6H8O7 is administered orally or parenterally

Note: Fentanyl is marketed under the trademark Actiq.

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