fentanyl

noun

fen·​ta·​nyl ˈfen-tə-ˌnil How to pronounce fentanyl (audio)
: a synthetic opioid narcotic analgesic C22H28N2O with pharmacological action similar to morphine that is administered transdermally as a skin patch and in the form of its citrate C22H28N2O·C6H8O7 is administered orally or parenterally (as by intravenous or epidural injection)

Examples of fentanyl in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
The outlets reported that detectives cited witnesses who said that that Cherry was aware of her mother's daily drug use — specifically of heroin laced with fentanyl. Charlotte Phillipp, PEOPLE, 26 Apr. 2026 Matthew Harris, of Oakland, allegedly confessed in full to the Wells Fargo bank robbery, expressing remorse and blaming his addiction to fentanyl, authorities said. Nate Gartrell, Mercury News, 25 Apr. 2026 His non-profit center, Get Your Drugs Tested, offers free drug checking and fentanyl screening to thousands, helping users avoid overdoses and death from the toxic drug supply. Matthew Carey, Deadline, 24 Apr. 2026 The Los Angeles County Medical Examiner classified his death as an accident caused by the effects of fentanyl. Jason Henry, Daily News, 24 Apr. 2026 See All Example Sentences for fentanyl

Word History

Etymology

probably alteration of phenethyl, a monovalent radical derived from ethylbenzine, from phen- + ethyl

First Known Use

1964, in the meaning defined above

Time Traveler
The first known use of fentanyl was in 1964

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Cite this Entry

“Fentanyl.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/fentanyl. Accessed 28 Apr. 2026.

Medical Definition

fentanyl

noun
fen·​ta·​nyl ˈfent-ᵊn-ˌil How to pronounce fentanyl (audio)
: a synthetic opioid narcotic analgesic C22H28N2O with pharmacological action similar to morphine that is administered transdermally as a skin patch and in the form of its citrate C22H28N2O·C6H8O7 is administered orally or parenterally

Note: Fentanyl is marketed under the trademark Actiq.

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