fentanyl

noun

fen·​ta·​nyl ˈfen-tə-ˌnil How to pronounce fentanyl (audio)
: a synthetic opioid narcotic analgesic C22H28N2O with pharmacological action similar to morphine that is administered transdermally as a skin patch and in the form of its citrate C22H28N2O·C6H8O7 is administered orally or parenterally (as by intravenous or epidural injection)

Examples of fentanyl in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
The Wallingford Police Department’s Crime Suppression Unit was investigating a man suspected of traveling to Wallingford to sell crack cocaine and fentanyl, according to police. Staff Report, Hartford Courant, 5 June 2026 The campaign is intended to warn visitors that fentanyl can be present in illicit drugs and counterfeit pills that resemble legitimate prescription medications, Schrock said. Ben Wheeler, Kansas City Star, 4 June 2026 Under his leadership, the office has become a state leader for its use of red-flag laws and championed the escalation of charges against reputed fentanyl dealers linked to fatal overdoses and parents whose neglect is alleged to have caused a child’s death. Robert Salonga, Mercury News, 3 June 2026 Alvarado-Gil has focused on fire insurance, fentanyl and farmers’ concerns. Corey Schmidt, Sacbee.com, 3 June 2026 See All Example Sentences for fentanyl

Word History

Etymology

probably alteration of phenethyl, a monovalent radical derived from ethylbenzine, from phen- + ethyl

First Known Use

1964, in the meaning defined above

Time Traveler
The first known use of fentanyl was in 1964

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Cite this Entry

“Fentanyl.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/fentanyl. Accessed 9 Jun. 2026.

Medical Definition

fentanyl

noun
fen·​ta·​nyl ˈfent-ᵊn-ˌil How to pronounce fentanyl (audio)
: a synthetic opioid narcotic analgesic C22H28N2O with pharmacological action similar to morphine that is administered transdermally as a skin patch and in the form of its citrate C22H28N2O·C6H8O7 is administered orally or parenterally

Note: Fentanyl is marketed under the trademark Actiq.

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