: a synthetic opioid narcotic analgesic C22H28N2O with pharmacological action similar to morphine that is administered transdermally as a skin patch and in the form of its citrate C22H28N2O·C6H8O7 is administered orally or parenterally (as by intravenous or epidural injection)

Examples of fentanyl in a Sentence

Recent Examples on the Web
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The man who killed rapper Pop Smoke got caught smuggling fentanyl into juvenile hall. Andrew J. Campa, Los Angeles Times, 15 Aug. 2026 Federal agents seized 61 guns, quantities of fentanyl, methamphetamine and cocaine, $98,000 in cash and 166 fighting dogs during the operation, according to the FBI. Brittany Miller, FOXNews.com, 14 Aug. 2026 Courtney McGee Cannon, 43, pleaded to three counts of possession with intent to distribute fentanyl. Laura Bauer, Kansas City Star, 14 Aug. 2026 Upon discovering that a nurse at the clinic was stealing vast amounts of fentanyl, Gabby seeks out other victims and leads a groundbreaking legal battle against Yale University. Nellie Andreeva, Deadline, 13 Aug. 2026 See All Example Sentences for fentanyl

Word History

Etymology

probably alteration of phenethyl, a monovalent radical derived from ethylbenzine, from phen- + ethyl

First Known Use

1964, in the meaning defined above

Time Traveler
The first known use of fentanyl was in 1964

Browse Nearby Words

Cite this Entry

“Fentanyl.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/fentanyl. Accessed 18 Aug. 2026.

Medical Definition

: a synthetic opioid narcotic analgesic C22H28N2O with pharmacological action similar to morphine that is administered transdermally as a skin patch and in the form of its citrate C22H28N2O·C6H8O7 is administered orally or parenterally

Note: Fentanyl is marketed under the trademark Actiq.

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