fen–phen

1:  a former diet drug combination of phentermine with either fenfluramine or dexfenfluramine that was used as an appetite suppressant in the treatment of obesity but was voluntarily withdrawn from the market in 1997 due to its association with heart disease—called also phen-fen

2:  an herbal preparation typically containing ephedra and Saint-John's-wort that was used as an appetite suppressant until one of its ingredients (ephedra) was banned in the U.S. by the FDA in 2004—called also phen-fen