factor V

noun

: a clotting factor produced primarily in the liver that circulates in an inactive form in blood plasma and in its activated form combines with factor X on the surface of platelets to accelerate the conversion of prothrombin to thrombin

Examples of factor V in a Sentence

Recent Examples on the Web
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The factor V Leiden mutation puts people at higher risk for developing blood clots. Dr. Keith Roach, oregonlive, 8 Feb. 2022

Word History

First Known Use

1947, in the meaning defined above

Time Traveler
The first known use of factor V was in 1947

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Cite this Entry

“Factor V.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/factor%20V. Accessed 4 Sep. 2025.

Medical Definition

factor V

noun
: a globulin clotting factor produced primarily in the liver that circulates in an inactive form in blood plasma and in its activated form combines with factor X on the surface of platelets to accelerate the conversion of prothrombin to thrombin

called also accelerator globulin, labile factor, proaccelerin

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