: a hemolytic disease of the fetus and newborn that occurs when the immune system of an Rh-negative mother produces antibodies to an antigen in the blood of an Rh-positive fetus which cross the placenta and destroy fetal erythrocytes and that is characterized by an increase in circulating erythroblasts and by jaundice
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Origin and Etymology of erythroblastosis fetalis
New Latin, fetal erythroblastosis
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First Known Use: circa 1934
in the meaning defined above
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: a hemolytic disease of the fetus and newborn that is characterized by an increase in circulating erythroblasts and by jaundice and that occurs when the immune system of an Rh-negative mother produces antibodies to an antigen in the blood of an Rh-positive fetus which cross the placenta and destroy fetal red blood cells — called also
hemolytic disease of the newborn, Rh disease
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