endothelium
noun
en·do·the·li·um
ˌen-də-ˈthē-lē-əm 
-dō-
plural endothelia
ˌen-də-ˈthē-lē-ə
-dō-
1
: an epithelium of mesodermal origin composed of a single layer of thin flattened cells that lines internal body cavities and the lumens of vessels
2
: the inner layer of the seed coat of some plants
Examples of endothelium in a Sentence
Recent Examples on the Web
The virus that causes covid can affect the vascular endothelium — specialized cells that line blood vessels and help with blood flow, Rasmussen said.
—
Kff Health News, Oc Register, 2 June 2025
Healthy endothelium cells also play a role in local cell growth and help prevent blood clotting.
—Sandee Lamotte, CNN Money, 28 May 2025
Aging and menopause contribute to the dysfunction of the endothelium (cells of blood vessels).
—Merve Ceylan, Health, 27 Dec. 2024
These complexes establish productive cellular infections in macrophages that result in the release of high concentrations of toxic NS1, a viral protein that damages cells' endothelium and produces dengue shock syndrome.
—Scientific American, 1 Jan. 2024
The corneal endothelium is a thin layer of cells that forms the inner lining of the cornea.
—William A. Haseltine, Forbes, 17 Feb. 2024
The innermost layer is known as the endothelial layer; exercise has been shown to influence the activity of the endothelium.
—Amber Sayer, Health, 25 Sep. 2023
Mamta Jain, $2.5 million for screening, treatment and prevention of Hepatocellular Cancer-Hepatitis C. Lance S. Terada, $1.05 million for autophagy and tumor endothelium.
—Dallas News, 16 Feb. 2023
The root of the problem is that even small amounts of the chemicals in cigarette smoke cause rapid inflammation in the endothelium, or lining, of blood vessels and in the lungs.
—Andrew Moseman, Discover Magazine, 10 Dec. 2010
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Kff Health News, Oc Register, 2 June 2025
Healthy endothelium cells also play a role in local cell growth and help prevent blood clotting.
—Sandee Lamotte, CNN Money, 28 May 2025
Aging and menopause contribute to the dysfunction of the endothelium (cells of blood vessels).
—Merve Ceylan, Health, 27 Dec. 2024
These complexes establish productive cellular infections in macrophages that result in the release of high concentrations of toxic NS1, a viral protein that damages cells' endothelium and produces dengue shock syndrome.
—Scientific American, 1 Jan. 2024
The corneal endothelium is a thin layer of cells that forms the inner lining of the cornea.
—William A. Haseltine, Forbes, 17 Feb. 2024
The innermost layer is known as the endothelial layer; exercise has been shown to influence the activity of the endothelium.
—Amber Sayer, Health, 25 Sep. 2023
Mamta Jain, $2.5 million for screening, treatment and prevention of Hepatocellular Cancer-Hepatitis C. Lance S. Terada, $1.05 million for autophagy and tumor endothelium.
—Dallas News, 16 Feb. 2023
The root of the problem is that even small amounts of the chemicals in cigarette smoke cause rapid inflammation in the endothelium, or lining, of blood vessels and in the lungs.
—Andrew Moseman, Discover Magazine, 10 Dec. 2010
Cite this Entry
“Endothelium.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/endothelium. Accessed 14 Jun. 2025.
Copy CitationMedical Definition
endothelium
noun
en·do·the·li·um
ˌen-də-ˈthē-lē-əm
plural endothelia
-lē-ə
: an epithelium of mesoblastic origin composed of a single layer of thin flattened cells that lines internal body cavities (as the serous cavities or the interior of the heart)
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