encephalopathy

noun

en·​ceph·​a·​lop·​a·​thy in-ˌse-fə-ˈlä-pə-thē How to pronounce encephalopathy (audio)
plural encephalopathies
: a disease of the brain
especially : one involving alterations of brain structure
encephalopathic adjective

Examples of encephalopathy in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Months later, she was diagnosed with encephalopathy, including some features of autism spectrum disorder, caused by a mitochondrial enzyme deficit. Judy Stone, Forbes.com, 3 Sep. 2025 This complication, called acute necrotizing encephalopathy, or ANE, carries a mortality rate of 27% despite intensive care and treatment, according to the new research. Katia Hetter, CNN Money, 19 Aug. 2025 Her mother had hepatic encephalopathy, an ammonia buildup in her body resulting from cirrhosis that causes brain dysfunction. Ariane Lange, Sacbee.com, 27 June 2025 Brady Crandall’s oldest daughter was born in 2020 with hypoxic-ischaemic encephalopathy (HIE). Jaclyn Greenberg, Parents, 8 Apr. 2025 See All Example Sentences for encephalopathy

Word History

First Known Use

1866, in the meaning defined above

Time Traveler
The first known use of encephalopathy was in 1866

Browse Nearby Words

Cite this Entry

“Encephalopathy.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/encephalopathy. Accessed 10 Sep. 2025.

Medical Definition

encephalopathy

noun
en·​ceph·​a·​lop·​a·​thy in-ˌsef-ə-ˈläp-ə-thē How to pronounce encephalopathy (audio)
plural encephalopathies
: a disease of the brain
especially : one involving alterations of brain structure
encephalopathic adjective

More from Merriam-Webster on encephalopathy

Last Updated: - Updated example sentences
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!