encephalopathy

noun

en·​ceph·​a·​lop·​a·​thy in-ˌse-fə-ˈlä-pə-thē How to pronounce encephalopathy (audio)
plural encephalopathies
: a disease of the brain
especially : one involving alterations of brain structure
encephalopathic adjective

Examples of encephalopathy in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Kalani has hypoxic-ischemic encephalopathy, a form of brain injury that affects muscle tone and mobility. Eva Remijan-Toba, Chicago Tribune, 10 Jan. 2026 Doctors at Mass General Hospital were able to diagnose her with acute necrotizing encephalopathy, a rare illness linked to the flu that causes the brain to swell and for the body to kill brain cells. Logan Hall, CBS News, 8 Jan. 2026 Gentry said kids with severe forms of autism were paid for encephalopathy until the government revised the definition in the mid-1990s. Erin Mansfield, USA Today, 11 Dec. 2025 More than 1 in 5 experience pneumonia, 1 in 50 experience convulsions and 1 in 150 experience encephalopathy, a group of brain diseases, the CDC reports. Max Rego, The Hill, 25 Nov. 2025 See All Example Sentences for encephalopathy

Word History

First Known Use

1866, in the meaning defined above

Time Traveler
The first known use of encephalopathy was in 1866

Browse Nearby Words

Cite this Entry

“Encephalopathy.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/encephalopathy. Accessed 14 Jan. 2026.

Medical Definition

encephalopathy

noun
en·​ceph·​a·​lop·​a·​thy in-ˌsef-ə-ˈläp-ə-thē How to pronounce encephalopathy (audio)
plural encephalopathies
: a disease of the brain
especially : one involving alterations of brain structure
encephalopathic adjective

More from Merriam-Webster on encephalopathy

Last Updated: - Updated example sentences
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!