encephalitis

noun

en·​ceph·​a·​li·​tis in-ˌse-fə-ˈlī-təs How to pronounce encephalitis (audio)
plural encephalitides in-ˌse-fə-ˈli-tə-ˌdēz How to pronounce encephalitis (audio)
: inflammation of the brain that is caused especially by infection with a virus (such as herpes simplex or West Nile virus) or less commonly by bacterial or fungal infection or autoimmune reaction

Note: Encephalitis may be asymptomatic or present with mild to severe symptoms (such as fever, headache, confusion, seizures, or loss of consciousness) sometimes progressing to coma or death.

encephalitic adjective

Examples of encephalitis in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Besides being nuisances, many types carry diseases including West Nile virus, encephalitis, and canine heartworm. Arricca Elin Sansone, Southern Living, 18 June 2026 In severe cases, UCHealth says the virus can cause serious complications such as encephalitis or meningitis. Christa Swanson, CBS News, 17 June 2026 In some cases, Powassan virus can cause severe disease, including encephalitis, an infection of the brain, or meningitis, an infection of membranes around the brain and spinal cord. Emily Vetter, USA Today, 16 June 2026 More serious outcomes can include pneumonia, encephalitis — or swelling of the brain — and, in rare cases, death, according to the CDC. Sacbee.com, 9 June 2026 See All Example Sentences for encephalitis

Word History

First Known Use

1843, in the meaning defined above

Time Traveler
The first known use of encephalitis was in 1843

Browse Nearby Words

Cite this Entry

“Encephalitis.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/encephalitis. Accessed 19 Jun. 2026.

Kids Definition

encephalitis

noun
en·​ceph·​a·​li·​tis in-ˌsef-ə-ˈlīt-əs How to pronounce encephalitis (audio)
(ˌ)en-
: inflammation of the brain
also : a disease marked by encephalitis

Medical Definition

encephalitis

noun
en·​ceph·​a·​li·​tis in-ˌsef-ə-ˈlīt-əs How to pronounce encephalitis (audio)
plural encephalitides -ˈlit-ə-ˌdēz How to pronounce encephalitis (audio)
: inflammation of the brain that is caused especially by infection with a virus (such as herpes simplex, varicella zoster, or West Nile virus) or less commonly by bacterial or fungal infection or autoimmune reaction

Note: Encephalitis may be asymptomatic or present with mild to severe symptoms (such as fever, headache, confusion, seizures, or loss of consciousness) sometimes progressing to coma or death.

encephalitic adjective

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