encephalitis

noun

en·​ceph·​a·​li·​tis in-ˌse-fə-ˈlī-təs How to pronounce encephalitis (audio)
plural encephalitides in-ˌse-fə-ˈli-tə-ˌdēz How to pronounce encephalitis (audio)
: inflammation of the brain that is caused especially by infection with a virus (such as herpes simplex or West Nile virus) or less commonly by bacterial or fungal infection or autoimmune reaction

Note: Encephalitis may be asymptomatic or present with mild to severe symptoms (such as fever, headache, confusion, seizures, or loss of consciousness) sometimes progressing to coma or death.

encephalitic adjective

Examples of encephalitis in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
In these cases, the virus affects the brain or nervous system and can cause encephalitis or meningitis, which can result in an infection of the brain or surrounding tissue, according to the CDC. Karen Garcia, Los Angeles Times, 30 June 2026 In severe cases, the virus affects the central nervous system, causing encephalitis (inflammation of the brain) or meningitis (inflammation of the membrane around the brain and spinal cords). Cara Lynn Shultz, PEOPLE, 29 June 2026 Though rare — there are up to 6,000 cases in the UK each year — encephalitis is often life-threatening. George Ramsay, New York Times, 23 June 2026 The rare but increasingly prevalent Powassan virus, spread mainly by the black-legged tick, can reach the brain and cause encephalitis. Kate Wong, Scientific American, 22 June 2026 See All Example Sentences for encephalitis

Word History

First Known Use

1843, in the meaning defined above

Time Traveler
The first known use of encephalitis was in 1843

Browse Nearby Words

Cite this Entry

“Encephalitis.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/encephalitis. Accessed 3 Jul. 2026.

Kids Definition

encephalitis

noun
en·​ceph·​a·​li·​tis in-ˌsef-ə-ˈlīt-əs How to pronounce encephalitis (audio)
(ˌ)en-
: inflammation of the brain
also : a disease marked by encephalitis

Medical Definition

encephalitis

noun
en·​ceph·​a·​li·​tis in-ˌsef-ə-ˈlīt-əs How to pronounce encephalitis (audio)
plural encephalitides -ˈlit-ə-ˌdēz How to pronounce encephalitis (audio)
: inflammation of the brain that is caused especially by infection with a virus (such as herpes simplex, varicella zoster, or West Nile virus) or less commonly by bacterial or fungal infection or autoimmune reaction

Note: Encephalitis may be asymptomatic or present with mild to severe symptoms (such as fever, headache, confusion, seizures, or loss of consciousness) sometimes progressing to coma or death.

encephalitic adjective

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