encephalitis

noun

en·​ceph·​a·​li·​tis in-ˌse-fə-ˈlī-təs How to pronounce encephalitis (audio)
plural encephalitides in-ˌse-fə-ˈli-tə-ˌdēz How to pronounce encephalitis (audio)
: inflammation of the brain that is caused especially by infection with a virus (such as herpes simplex or West Nile virus) or less commonly by bacterial or fungal infection or autoimmune reaction

Note: Encephalitis may be asymptomatic or present with mild to severe symptoms (such as fever, headache, confusion, seizures, or loss of consciousness) sometimes progressing to coma or death.

encephalitic adjective

Examples of encephalitis in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Those infected in South Carolina who haven’t yet developed encephalitis may yet do so. Meghan Bartels, Scientific American, 5 Feb. 2026 Along with the telltale rash, measles can cause a high fever, cough, pneumonia, swelling of the brain (encephalitis), and death. Cara Lynn Shultz, PEOPLE, 3 Feb. 2026 Measles can result in serious complications, including pneumonia, encephalitis and death. Eve Chen, USA Today, 3 Feb. 2026 The virus can lead to severe symptoms, including disorientation, drowsiness, seizures or encephalitis, which is inflammation of the brain. Mary Kekatos, ABC News, 29 Jan. 2026 See All Example Sentences for encephalitis

Word History

First Known Use

1843, in the meaning defined above

Time Traveler
The first known use of encephalitis was in 1843

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Cite this Entry

“Encephalitis.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/encephalitis. Accessed 13 Feb. 2026.

Kids Definition

encephalitis

noun
en·​ceph·​a·​li·​tis in-ˌsef-ə-ˈlīt-əs How to pronounce encephalitis (audio)
(ˌ)en-
: inflammation of the brain
also : a disease marked by encephalitis

Medical Definition

encephalitis

noun
en·​ceph·​a·​li·​tis in-ˌsef-ə-ˈlīt-əs How to pronounce encephalitis (audio)
plural encephalitides -ˈlit-ə-ˌdēz How to pronounce encephalitis (audio)
: inflammation of the brain that is caused especially by infection with a virus (such as herpes simplex, varicella zoster, or West Nile virus) or less commonly by bacterial or fungal infection or autoimmune reaction

Note: Encephalitis may be asymptomatic or present with mild to severe symptoms (such as fever, headache, confusion, seizures, or loss of consciousness) sometimes progressing to coma or death.

encephalitic adjective

More from Merriam-Webster on encephalitis

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