encephalitis

noun

en·​ceph·​a·​li·​tis in-ˌse-fə-ˈlī-təs How to pronounce encephalitis (audio)
plural encephalitides in-ˌse-fə-ˈli-tə-ˌdēz How to pronounce encephalitis (audio)
: inflammation of the brain that is caused especially by infection with a virus (such as herpes simplex or West Nile virus) or less commonly by bacterial or fungal infection or autoimmune reaction

Note: Encephalitis may be asymptomatic or present with mild to severe symptoms (such as fever, headache, confusion, seizures, or loss of consciousness) sometimes progressing to coma or death.

encephalitic adjective

Examples of encephalitis in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
A number of viruses can cause encephalitis, including the herpes simplex virus (HSV) type 1, or HSV-1, which can cause cold sores and painful blisters, the BBC noted. Adam England, PEOPLE, 13 Apr. 2026 The Directorate General of Health Services said unvaccinated children or those who have not completed ​the two-dose measles schedule face the greatest risk ​and ⁠that malnourished children are particularly prone to severe complications such as pneumonia and encephalitis. Reuters, NBC news, 2 Apr. 2026 In September 1879, the girl died of viral encephalitis — presumed to have been transmitted by a mosquito — just weeks before her 13th birthday. Camila Pedrosa, Sacbee.com, 31 Mar. 2026 Roughly 1 in 20 children with measles develops pneumonia, and about 1 out of every 1,000 children who have measles infections also will have encephalitis. Kristen Jordan Shamus, Freep.com, 19 Mar. 2026 See All Example Sentences for encephalitis

Word History

First Known Use

1843, in the meaning defined above

Time Traveler
The first known use of encephalitis was in 1843

Browse Nearby Words

Cite this Entry

“Encephalitis.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/encephalitis. Accessed 15 Apr. 2026.

Kids Definition

encephalitis

noun
en·​ceph·​a·​li·​tis in-ˌsef-ə-ˈlīt-əs How to pronounce encephalitis (audio)
(ˌ)en-
: inflammation of the brain
also : a disease marked by encephalitis

Medical Definition

encephalitis

noun
en·​ceph·​a·​li·​tis in-ˌsef-ə-ˈlīt-əs How to pronounce encephalitis (audio)
plural encephalitides -ˈlit-ə-ˌdēz How to pronounce encephalitis (audio)
: inflammation of the brain that is caused especially by infection with a virus (such as herpes simplex, varicella zoster, or West Nile virus) or less commonly by bacterial or fungal infection or autoimmune reaction

Note: Encephalitis may be asymptomatic or present with mild to severe symptoms (such as fever, headache, confusion, seizures, or loss of consciousness) sometimes progressing to coma or death.

encephalitic adjective

More from Merriam-Webster on encephalitis

Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!

More from Merriam-Webster