encephalitis

noun

en·​ceph·​a·​li·​tis in-ˌse-fə-ˈlī-təs How to pronounce encephalitis (audio)
plural encephalitides in-ˌse-fə-ˈli-tə-ˌdēz How to pronounce encephalitis (audio)
: inflammation of the brain that is caused especially by infection with a virus (such as herpes simplex or West Nile virus) or less commonly by bacterial or fungal infection or autoimmune reaction

Note: Encephalitis may be asymptomatic or present with mild to severe symptoms (such as fever, headache, confusion, seizures, or loss of consciousness) sometimes progressing to coma or death.

encephalitic adjective

Examples of encephalitis in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Measles can result in serious complications, including pneumonia, encephalitis and death. Eve Chen, USA Today, 3 Feb. 2026 The virus can lead to severe symptoms, including disorientation, drowsiness, seizures or encephalitis, which is inflammation of the brain. Mary Kekatos, ABC News, 29 Jan. 2026 Vaccines eradicated smallpox and were thought to have done so with polio and measles, which can cause encephalitis and other potentially fatal complications. Orlando Sentinel, The Orlando Sentinel, 28 Jan. 2026 There are serious complications of pneumonia (1 in 20), encephalitis (brain swelling) in 1/1,000, deafness in many and deaths in 1-3/1,000. Judy Stone, Forbes.com, 24 Jan. 2026 See All Example Sentences for encephalitis

Word History

First Known Use

1843, in the meaning defined above

Time Traveler
The first known use of encephalitis was in 1843

Browse Nearby Words

Cite this Entry

“Encephalitis.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/encephalitis. Accessed 9 Feb. 2026.

Kids Definition

encephalitis

noun
en·​ceph·​a·​li·​tis in-ˌsef-ə-ˈlīt-əs How to pronounce encephalitis (audio)
(ˌ)en-
: inflammation of the brain
also : a disease marked by encephalitis

Medical Definition

encephalitis

noun
en·​ceph·​a·​li·​tis in-ˌsef-ə-ˈlīt-əs How to pronounce encephalitis (audio)
plural encephalitides -ˈlit-ə-ˌdēz How to pronounce encephalitis (audio)
: inflammation of the brain that is caused especially by infection with a virus (such as herpes simplex, varicella zoster, or West Nile virus) or less commonly by bacterial or fungal infection or autoimmune reaction

Note: Encephalitis may be asymptomatic or present with mild to severe symptoms (such as fever, headache, confusion, seizures, or loss of consciousness) sometimes progressing to coma or death.

encephalitic adjective

More from Merriam-Webster on encephalitis

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