efficacy

noun

ef·​fi·​ca·​cy ˈe-fi-kə-sē How to pronounce efficacy (audio)
plural efficacies
Synonyms of efficacynext
: the power to produce a result or effect
increased teacher efficacy in classroom management
The efficacy of this treatment has not yet been proved.
In the upcoming … clinical trial, researchers will further investigate the efficacy and safety of the vaccine.Julia Landwehr

Examples of efficacy in a Sentence

In the planner's view, Rumsfeld had two goals: to demonstrate the efficacy of precision bombing and to "do the war on the cheap." Seymour M. Hersh, New Yorker, 7 Apr. 2003
Vaccines exist, but their efficacy against aerosolized plague is unknown. Sharon Begley et al., Newsweek, 8 Oct. 2001
efficacy does not have to be demonstrated before homeopathic products are marketed. Alison Abbott et al., Nature, 26 Sept. 1996
questioned the efficacy of the alarms in actually preventing auto theft
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Over time, this strengthens self-efficacy and mutual respect, both of which are central to long-term relational stability. Mark Travers, Forbes.com, 24 Jan. 2026 Isaacson noted there are decades of research on the efficacy of vaccinations, but things started to change with the COVID-19 pandemic. Mike Danahey, Chicago Tribune, 24 Jan. 2026 But in 2015, Holmes was exposed for misleading investors and misrepresenting the efficacy of Theranos’s technology following a series of articles in the Wall Street Journal. Jacqueline Munis, Fortune, 23 Jan. 2026 Freezing can also alter the physical properties of medications, leading to inconsistent dosing and reduced efficacy. Elissa Robinson, Detroit Free Press, 23 Jan. 2026 See All Example Sentences for efficacy

Word History

Etymology

borrowed from Latin efficācia, from efficāc-, efficāx "capable of fulfilling a function, efficacious" + -ia -y entry 2

First Known Use

1527, in the meaning defined above

Time Traveler
The first known use of efficacy was in 1527

Browse Nearby Words

Cite this Entry

“Efficacy.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/efficacy. Accessed 28 Jan. 2026.

Kids Definition

efficacy

noun
ef·​fi·​ca·​cy ˈef-i-kə-sē How to pronounce efficacy (audio)
plural efficacies
: the power to produce a desired result

More from Merriam-Webster on efficacy

Last Updated: - Updated example sentences
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!