plural E. coli
: an enterobacterium (Escherichia coli) that is used in public health as an indicator of fecal pollution (as of water or food) and in medicine and genetics as a research organism and that occurs in various strains that may live as harmless inhabitants of the human lower intestine or may produce a toxin causing intestinal illness see enterobacterium illustration

Examples of E. coli in a Sentence

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The samples are then tested in a laboratory to detect the presence of genetic material from Enterococci — bacteria that, like E. coli, live in the intestines of warm-blooded animals such as humans. Adriana Pérez, Chicago Tribune, 22 Aug. 2025 They are used as an indicator that other, potentially harmful, fecal bacteria (indicated by the E. coli species) could be present. Jalen Williams, Freep.com, 22 Aug. 2025 Three village of Germantown wells that earlier tested positive for bacterial contaminants each tested negative for E. coli, officials reported Aug. 19. Cathy Kozlowicz, jsonline.com, 20 Aug. 2025 The lawsuit alleges that the raw milk producer and seller are liable because the product contained Campylobacter and E. coli and failed to give adequate warnings of the product’s dangers. Mark Harper, USA Today, 19 Aug. 2025 See All Example Sentences for E. coli

Word History

First Known Use

1925, in the meaning defined above

Time Traveler
The first known use of E. coli was in 1925

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Cite this Entry

“E. coli.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/E.%20coli. Accessed 29 Aug. 2025.

Kids Definition

E. coli

noun
plural E. coli
: a bacterium in the shape of a short rod that may cause intestinal illness
Etymology

short for Escherichia coli, the taxonomic name in biology

Medical Definition

E. coli

noun
ˌē-ˈkō-ˌlī
plural E. coli also E. colis
: a straight rod-shaped gram-negative bacterium (Escherichia coli of the family Enterobacteriaceae) that is used in public health as an indicator of fecal pollution (as of water or food) and in medicine and genetics as a research organism and that occurs in various strains that may live as harmless inhabitants of the human lower intestine or may produce a toxin causing intestinal illness marked especially by diarrhea
one million acid-resistant E. coli per gram of fecesJohn Schwartz
this E. coli can survive … longer than all the other E. colisEd Geldreich
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