dys·tro·phin
| \ ˈdi-strə-ˌfin
\
\
Definition of dystrophin
: a protein that is associated with a transmembrane complex of skeletal muscle cells and that is absent in Duchenne muscular dystrophy and deficient or defective in Becker muscular dystrophy
Examples of dystrophin in a Sentence
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In a study involving patients with Duchenne muscular dystrophy, 12 weeks of treatment with the Wave drug called suvodirsen failed to increase levels of dystrophin compared to baseline, the company said.
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BostonGlobe.com, 17 Dec. 2019
Duchenne is a rare fatal neuromuscular disease caused by mutations in the dystrophin gene that result in a progressive loss of muscle function and weakness, including in the heart and skeleton.
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BostonGlobe.com, 24 Dec. 2019
The guide RNAs were designed to trigger production of a missing protein called dystrophin.
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Sara Reardon, Scientific American, 5 Feb. 2020
In a study involving patients with Duchenne muscular dystrophy, 12 weeks of treatment with the Wave drug called suvodirsen failed to increase levels of dystrophin compared to baseline, the company said.
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BostonGlobe.com, 17 Dec. 2019
In a study involving patients with Duchenne muscular dystrophy, 12 weeks of treatment with the Wave drug called suvodirsen failed to increase levels of dystrophin compared to baseline, the company said.
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Adam Feuerstein, STAT, 16 Dec. 2019
In a clinical trial, Vyondys 53 produced a small increase in an important muscle protein called dystrophin that children with Duchenne lack.
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BostonGlobe.com, 24 Dec. 2019
In a clinical trial, Sarepta’s drug produced a small increase in an important muscle protein called dystrophin that is normally missing in children with Duchenne.
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Damian Garde, STAT, 12 Dec. 2019
Instead, the Wave drug made no dystrophin protein at all, which raises serious questions about the viability of the company’s entire chemistry platform.
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BostonGlobe.com, 17 Dec. 2019
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“Dystrophin.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/dystrophin. Accessed 28 Sep. 2021.
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More Definitions for dystrophin
dystrophin
noun
dys·tro·phin
| \ ˈdis-trə-ˌfin
\
\
Medical Definition of dystrophin
: a protein of high molecular weight that is associated with a transmembrane glycoprotein complex of skeletal muscle cells and is absent in Duchenne muscular dystrophy and deficient or of abnormal molecular weight in Becker muscular dystrophy
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The first known use of dystrophin was in 1987
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