dis·​equi·​lib·​ri·​um (ˌ)dis-ˌē-kwə-ˈli-brē-əm How to pronounce disequilibrium (audio)
: loss or lack of equilibrium

Examples of disequilibrium in a Sentence

The condition is caused by a disequilibrium in the brain's chemistry.
Recent Examples on the Web One of my ideas was to place a figure from the Age of Enlightenment, a humanist, in a sort of psychic disequilibrium. Anderson Tepper, Los Angeles Times, 13 Sep. 2023 If disequilibrium equals opportunity, Zero Party Data Analytics just might provide both retailers and brands with a …new compass. Gary Drenik, Forbes, 8 June 2022 In contrast additive effects are less sensitive to decay in linkage disequilibrium, which measures the association of alleles across genes, so that one marker may serve as a signal for the presence of another variant down or up the genome. Razib Khan, Discover Magazine, 5 Mar. 2013 From first principles, this approach can replicate the most obvious example of atmospheric disequilibrium today on our planet—the presence of oxygen and traces of methane (the latter being the gentle exhalations of the once mighty methanogen biosphere). Lee Billings, Scientific American, 24 Jan. 2018 Using the most sensitive measure of recent consanguinity, a statistic of run of homozygosity pruned of markers in linkage disequilibrium, the authors did not find a strong effect of magnitude of inbreeding increasing the depression. Razib Khan, Discover Magazine, 20 July 2012 That's called disequilibrium. David Meyer, Fortune, 11 Mar. 2022 Billy's severe psychotic episodes point to a brain in disequilibrium and, correspondingly, to the need for drugs and treatments to alter this pathology as a basic standard of care. Matthew M. Kurtz, Scientific American, 1 Mar. 2023 So linkage disequilibrium, where genetic variants (alleles) across loci (genes) exhibit non-random statistical associations, varies over time as the correlations decay due to recombination. Razib Khan, Discover Magazine, 19 Jan. 2011 See More

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'disequilibrium.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History

First Known Use

1840, in the meaning defined above

Time Traveler
The first known use of disequilibrium was in 1840

Dictionary Entries Near disequilibrium

Cite this Entry

“Disequilibrium.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/disequilibrium. Accessed 30 Sep. 2023.

Medical Definition


dis·​equi·​lib·​ri·​um (ˌ)dis-ˌē-kwə-ˈlib-rē-əm, -ˌek-wə- How to pronounce disequilibrium (audio)
plural disequilibriums or disequilibria -rē-ə How to pronounce disequilibrium (audio)
: loss or lack of equilibrium
ionic disequilibrium in a resting nerve cell
emotional disequilibrium

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