de·​spic·​a·​bil·​i·​ty | \də̇ˌspikəˈbilətē, -ətē, -i also ˌdespə̇k- or ˌdeˌspik-\
plural despicabilities

Definition of despicability 

: a despicable quality or aspect … when writers present to the world someone as unsympathetic as John Self or Humbert Humbert, they tend to sweeten the pill by offsetting the character's despicability with likeable qualities: irony, japery, or a fancy prose style.— David Annand, The (London) Sunday Telegraph, 4 May 2014

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noxious or harmful

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