depolarization
noun
de·po·lar·i·za·tion
(ˌ)dē-ˌpō-lə-rə-ˈzā-shən 
1
: the process of depolarizing something or the state of being depolarized
2
physiology
: loss of the difference in charge between the inside and outside of the plasma membrane of a muscle or nerve cell due to a change in permeability and migration of sodium ions to the interior
… partial depolarization of the ventricular tissue resulting from rapid conduction of the electrical impulse from the atrium to the ventricle …—
Mark S. Link
Mark S. LinkExamples of depolarization in a Sentence
Recent Examples on the Web
The Champaign News-Gazette, for example, invited the local chapter of Braver Angels to write guest columns about depolarization.
—Chicago Tribune, 1 Apr. 2025
So just membrane depolarization is sufficient to promote the growth of the cancer.
—Ingrid Wickelgren, Scientific American, 14 Feb. 2025
In cases where no party affiliation was given, the depolarization was smaller (0.15 standard deviations).
—John Timmer, Ars Technica, 21 Aug. 2023
These leaders believe that no matter the corporate culture, executive ideology, or tolerance for issue engagement, more businesses can add depolarization skills to their toolkits.
—Tucker Eskew, Fortune, 19 July 2023
Trusted information is one of five bipartisan pillars More Perfect is built upon, joining civics education, national service, depolarization, and reliable elections.
—Tucker Eskew, Fortune, 19 July 2023
In any case, far from hastening fatigue, lactate accumulation in the muscles actually delays fatigue by mitigating the effects of a phenomenon known as depolarization.
—Matt Fitzgerald, Outside Online, 24 Jan. 2014
So, the decoupling and the sort of depolarization (ph) of the world would lead to less economic growth, less prosperity in the world, more poverty across the world.
—CBS News, 16 Apr. 2023
When the researchers counteracted the depolarization, some of the tumors disappeared.
—Matthew Hutson, The New Yorker, 3 May 2021
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Chicago Tribune, 1 Apr. 2025
So just membrane depolarization is sufficient to promote the growth of the cancer.
—Ingrid Wickelgren, Scientific American, 14 Feb. 2025
In cases where no party affiliation was given, the depolarization was smaller (0.15 standard deviations).
—John Timmer, Ars Technica, 21 Aug. 2023
These leaders believe that no matter the corporate culture, executive ideology, or tolerance for issue engagement, more businesses can add depolarization skills to their toolkits.
—Tucker Eskew, Fortune, 19 July 2023
Trusted information is one of five bipartisan pillars More Perfect is built upon, joining civics education, national service, depolarization, and reliable elections.
—Tucker Eskew, Fortune, 19 July 2023
In any case, far from hastening fatigue, lactate accumulation in the muscles actually delays fatigue by mitigating the effects of a phenomenon known as depolarization.
—Matt Fitzgerald, Outside Online, 24 Jan. 2014
So, the decoupling and the sort of depolarization (ph) of the world would lead to less economic growth, less prosperity in the world, more poverty across the world.
—CBS News, 16 Apr. 2023
When the researchers counteracted the depolarization, some of the tumors disappeared.
—Matthew Hutson, The New Yorker, 3 May 2021
Cite this Entry
“Depolarization.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/depolarization. Accessed 8 Jul. 2025.
Copy CitationMedical Definition
depolarization
noun
de·po·lar·iza·tion
variants
or British depolarisation
: loss of polarization
especially
: loss of the difference in charge between the inside and outside of the plasma membrane of a muscle or nerve cell due to a change in permeability and migration of sodium ions to the interior
… partial depolarization of the ventricular tissue resulting from rapid conduction of the electrical impulse from the atrium to the ventricle … —Mark S. Link, The New England Journal of Medicine
Mark S. Link, The New England Journal of Medicine Love words? Need even more definitions?
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