depolarization

noun

de·po·lar·i·za·tion | \(ˌ)dē-ˌpō-lə-rə-ˈzā-shən

Definition of depolarization

1 : the process of depolarizing something or the state of being depolarized

2 physiology : loss of the difference in charge between the inside and outside of the plasma membrane of a muscle or nerve cell due to a change in permeability and migration of sodium ions to the interior … partial depolarization of the ventricular tissue resulting from rapid conduction of the electrical impulse from the atrium to the ventricle …— Mark S. Link

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The first known use of depolarization was circa 1814

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depolarization

noun

de·po·lar·iza·tion

variants: or British depolarisation \(ˌ)dē-ˌpō-lə-rə-ˈzā-shən

Medical Definition of depolarization

: loss of polarization especially : loss of the difference in charge between the inside and outside of the plasma membrane of a muscle or nerve cell due to a change in permeability and migration of sodium ions to the interior … partial depolarization of the ventricular tissue resulting from rapid conduction of the electrical impulse from the atrium to the ventricle … — Mark S. Link, The New England Journal of Medicine, 11 Oct. 2012