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demethylate

verb

de·​meth·​yl·​ate (ˈ)dē-ˈme-thə-ˌlāt How to pronounce demethylate (audio)
demethylated; demethylating; demethylates

transitive verb

: to remove a methyl group from (a chemical compound)
demethylation noun

Word History

First Known Use

1926, in the meaning defined above

Time Traveler
The first known use of demethylate was in 1926

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Cite this Entry

“Demethylate.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/demethylate. Accessed 26 Nov. 2025.

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