Definition of cuaguayote
: a small Mexican tree (Pileus mexicanus) of the family Caricaceae having leaves and fruit that yield a proteolytic enzyme
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Origin and Etymology of cuaguayote
Mexican Spanish cuaguayote, cuahuayote, from Nahuatl cuauhayotli, literally, tree gourd, from cuauh- (from cuahuitl tree) + ayotli gourd
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