cross-tolerance

noun
cross-tol·er·ance | \ˈkrȯs-ˈtäl-rən(t)s, -ˈtä-lə-\

Definition of cross-tolerance 

: tolerance or resistance to a drug that develops through continued use of another drug with similar pharmacological action

First Known Use of cross-tolerance

circa 1923, in the meaning defined above

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The first known use of cross-tolerance was circa 1923

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cross-tolerance

noun
cross-tol·er·ance | \ˈkrȯ-ˈstäl(-ə)-rən(t)s \

Medical Definition of cross-tolerance 

: tolerance or resistance to a drug that develops through continued use of another drug with similar pharmacological action

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