Merriam-Webster Logo
SINCE 1828
Menu
×

An Encyclopædia Britannica Company

cross-resistance

noun cross-re·sis·tance \ ˌkrȯs-ri-ˈzi-stən(t)s \
See What's Trending Now See More Trending Words

Definition of cross-resistance

: tolerance (as of a bacterium) to a usually toxic substance (such as an antibiotic) that is acquired not as a result of direct exposure but by exposure to a related substance

First Known Use of cross-resistance

1946

in the meaning defined above

See Words from the same year
NEW! Time Traveler

Medical Dictionary

cross-resistance

noun cross-re·sis·tance \ ˌkrȯs-ri-ˈzis-tən(t)s \

medical Definition of cross-resistance

: tolerance (as of a bacteria, malignant cell, or insect) to a usually toxic substance (as an antibiotic, chemotherapy drug, or pesticide) that is acquired not as a result of direct exposure but by exposure to a related substance
  • The history of drug resistance in falciparum malaria suggests that these compounds may also enjoy only a short-lived glory and that cross-resistance with related compounds can be expected.
  • —David J. Wyler,  The Journal of the American Medical Association,  11 May 1984
  • … paclitaxel and docetaxel are being incorporated into adjuvant regimens on the basis of their antitumor activity in advanced breast cancer and the absence of cross-resistance with doxorubicin.
  • —Charles L. Shapiro, et al., The New England Journal of Medicine,  28 June 2001

Seen and Heard

What made you want to look up cross-resistance? Please tell us where you read or heard it (including the quote, if possible).

show hide

Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!

WORD OF THE DAY

mollycoddle

play

to treat with excessive attention

Get Word of the Day daily email!

TRENDING NOW

  1. pansexual 'sexual desire or attraction...not limited to a particular gender identity or sexual orientation'

  2. symbiote 'an organism living in symbiosis'

  3. charlatan 'faker or fraud'

  4. lowlife 'a person of low moral character'

  5. kakistocracy 'government by the worst people'

SEE ALL

BROWSE DICTIONARY

cross-resistance

Test Your Vocabulary

April 2018 Words of the Day Quiz

  • rain-on-rainbow-umbrella
  • Which is the best synonym of traduce?
Spell It

Can you spell these 10 commonly misspelled words?

TAKE THE QUIZ
Add Diction

Test Your Knowledge - and learn some interesting things along the way.

TAKE THE QUIZ

Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!

Words at Play

alt-5ae23d5d250bd
'Rather Than': Is It a Conjunction or Preposition?

It's both, and here's why.

alt-5ae227cf365c4
‘Magnate’ and ‘Magnet’: Poles Apart

This is kind of a Big Deal

image278155226
All the Hits

8 obscure words for bodily harm

alt-5adf93a49b0b2
The Fossil Encased in "Case In Point"

"In point" only lives in this phrase.

Ask the Editors

image1760257654
2017 Word of the Year: Behind the Scenes

How we chose 'feminism'

video-title-words-of-the-year-1066
Words of the Year: 1066

Or, Why Pig Meat is Called 'Pork' and Cow Meat is Called 'Beef'

video-literally
Literally

How to use a word that (literally) drives some people nuts.

video-his-or-her
Is Singular 'They' a Better Choice?

The awkward case of 'his or her'

Word Games

rain-on-rainbow-umbrella
April 2018 Words of the Day Quiz

The rhyming verb edition.

Take the quiz
image1926873504
Odd Habits and Quirks Quiz

Test your knowledge of strange human behaviors.

Take the quiz
Spell It
Spell It

Can you spell these 10 commonly misspelled words?

Take the quiz
Add Diction
Add Diction

Build a chain of words by adding one letter at a time.

Play the game