Definition of coyotillo
: a shrub (Karwinskia humboldtiana) of the buckthorn family of the southwestern U.S. and Mexico having poisonous berries
Origin and Etymology of coyotillo
Mexican Spanish, diminutive of coyote
First Known Use: circa 1892See Words from the same year
Seen and Heard
What made you want to look up coyotillo? Please tell us where you read or heard it (including the quote, if possible).