co·​tin·​ine | \ ˈkō-tə-ˌnēn How to pronounce cotinine (audio) , -ˌnīn How to pronounce cotinine (audio) \

Definition of cotinine

: an alkaloid C10H12N2O that is the principal metabolite of nicotine

Examples of cotinine in a Sentence

Recent Examples on the Web The lab noted positive findings for caffeine, cotinine and Delta-9 carboxy THC. al, 15 Oct. 2021 According to the report, the amounts of caffeine and cotinine found in his system are not typically toxicologically significant. al, 15 Oct. 2021 According to the Centers for Disease Control and Prevention, cotinine is a compound formed after the chemical nicotine enters the body. al, 15 Oct. 2021 The study defined tobacco exposure as a child reporting smoking, living with a smoker or having serum cotinine levels, which measures recent exposure to nicotine, greater than 0.05 micrograms per liter. Megan Marples, CNN, 25 Feb. 2021 Young people's blood was tested for levels of serum cotinine, a metabolite of nicotine; 0.05 to 10 nanograms per milliliter identified exposure to secondhand smoke. Allen Kim, CNN, 15 Aug. 2019 For verification, participants took a saliva test that detects cotinine, an indicator of nicotine exposure. Catherine Ho, San Francisco Chronicle, 24 May 2018 See More

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'cotinine.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

First Known Use of cotinine

1893, in the meaning defined above

History and Etymology for cotinine

probably anagram of nicotine

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Time Traveler for cotinine

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The first known use of cotinine was in 1893

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Cite this Entry

“Cotinine.” Dictionary, Merriam-Webster, Accessed 25 Jun. 2022.

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More Definitions for cotinine


co·​tin·​ine | \ ˈkōt-ᵊn-ˌēn How to pronounce cotinine (audio) , -ˌīn How to pronounce cotinine (audio) \

Medical Definition of cotinine

: an alkaloid C10H12N2O that is the principal metabolite of nicotine and is widely used as an indicator of recent exposure to nicotine


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