cocaine

noun

co·​caine kō-ˈkān How to pronounce cocaine (audio)
ˈkō-ˌkān
: a bitter crystalline alkaloid C17H21NO4 obtained from coca leaves that is used especially in the form of its hydrochloride medically as a topical anesthetic and illicitly for its euphoric effects and that may result in a compulsive psychological need

Examples of cocaine in a Sentence

Recent Examples on the Web
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Outside the show, Cloud died in July 2023 at age 25 from an accidental overdose of a mix of fentanyl, methamphetamine, cocaine, and benzodiazepines, per the Alameda County Coroner's Office at the time. Joey Nolfi, Entertainment Weekly, 13 Apr. 2026 Such activities cause dopamine to be released at around 50-100% of normal levels, while cocaine comparatively increases dopamine by 350%, and methamphetamine by 1500%. William Proctor, The Orlando Sentinel, 11 Apr. 2026 Greek police seized nearly 600 pounds of cocaine inside a banana shipment in August 2025. Kerry Breen, CBS News, 11 Apr. 2026 The cartel used his business to ship cocaine hidden inside packages of frozen vegetables to the United States. Jay Weaver, Miami Herald, 10 Apr. 2026 See All Example Sentences for cocaine

Word History

First Known Use

1860, in the meaning defined above

Time Traveler
The first known use of cocaine was in 1860

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Cite this Entry

“Cocaine.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/cocaine. Accessed 21 Apr. 2026.

Kids Definition

cocaine

noun
co·​caine kō-ˈkān How to pronounce cocaine (audio)
ˈkō-ˌkān
: a bitter habit-forming drug obtained from coca leaves and used in medicine to deaden pain and illegally for its euphoric effects

Medical Definition

cocaine

noun
co·​caine kō-ˈkān, ˈkō-ˌ How to pronounce cocaine (audio)
: a bitter crystalline alkaloid C17H21NO4 obtained from coca leaves that is used medically especially in the form of its hydrochloride C17H21NO4·HCl as a topical anesthetic and illicitly for its euphoric effects and that may result in a compulsive psychological need

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