cocaine

noun

: a bitter crystalline alkaloid C17H21NO4 obtained from coca leaves that is used especially in the form of its hydrochloride medically as a topical anesthetic and illicitly for its euphoric effects and that may result in a compulsive psychological need

Examples of cocaine in a Sentence

Recent Examples on the Web
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The 40-year-old Crowley also talked about his own experience growing up in poverty and with working-class parents who battled substance abuse and mental health issues during the city's crack-cocaine epidemic. — Maayan Silver, NPR, 4 Nov. 2026 Sign Up for Our Free Daily Newsletter The ancient Inca sacrificed children who were drugged with cocaine, a powerful hallucinogen and, in some cases, alcohol, according to a new study in Antiquity. — Adam Kovac, Scientific American, 3 Nov. 2026 The sniffling wasn’t from cocaine Many viewers speculated that Evans began using cocaine after moving to Texas, pointing to his frequent sniffling as evidence of his drug use. — Wesley Stenzel, Entertainment Weekly, 3 Nov. 2026 Leijdekkers is considered to be one of the key players in the international cocaine trade. — CBS News, 2 Nov. 2026 See All Example Sentences for cocaine

Word History

First Known Use

1860, in the meaning defined above

Time Traveler
The first known use of cocaine was in 1860

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Cite this Entry

“Cocaine.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/cocaine. Accessed 10 Nov. 2026.

Kids Definition

cocaine

noun
: a bitter habit-forming drug obtained from coca leaves and used in medicine to deaden pain and illegally for its euphoric effects

Medical Definition

: a bitter crystalline alkaloid C17H21NO4 obtained from coca leaves that is used medically especially in the form of its hydrochloride C17H21NO4·HCl as a topical anesthetic and illicitly for its euphoric effects and that may result in a compulsive psychological need

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