clozapine

noun

clo·​za·​pine ˈklō-zə-ˌpēn How to pronounce clozapine (audio)
: an antipsychotic drug C18H19ClN4 used in the treatment of schizophrenia

Examples of clozapine in a Sentence

Recent Examples on the Web Currently, the drug clozapine is the only option for treatment-resistant schizophrenia. Claire Bugos, Verywell Health, 30 Sep. 2024 The center is also participating in the clozapine study. Angela Roberts, Baltimore Sun, 1 July 2024 Other countries have been more discerning about clozapine’s public health calculus, resulting in less-stringent monitoring regulations and more widespread clozapine prescribing. Brian Barnett, STAT, 9 May 2022 To prevent and rapidly address cases of agranulocytosis, the FDA requires clozapine’s manufacturers to jointly administer the clozapine REMS program. Brian Barnett, STAT, 9 May 2022 Frustratingly, the antipsychotic that works best against schizophrenia’s symptoms—clozapine, which emerged in the late 1980s—can have the nastiest unwanted effects, including weight gain, diabetes, and excessive sleepiness. WIRED, 10 Feb. 2023 For them, clozapine is the gold standard treatment. Brian Barnett, STAT, 9 May 2022 Many medications can cause excess salivation, such as clonozapam (Klonopin) and clozapine (Clozaril). Dr. Keith Roach, oregonlive, 7 Oct. 2021 He was evaluated by a doctor, now a defendant in the lawsuit, who did not prescribe clozapine. Sydney Czyzon, Milwaukee Journal Sentinel, 3 July 2019

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'clozapine.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History

Etymology

International Scientific Vocabulary chlor- + -zapine, alteration of -azepine (as in benzodiazepine)

First Known Use

1970, in the meaning defined above

Time Traveler
The first known use of clozapine was in 1970

Dictionary Entries Near clozapine

Cite this Entry

“Clozapine.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/clozapine. Accessed 31 Oct. 2024.

Medical Definition

clozapine

noun
clo·​za·​pine ˈklō-zə-ˌpēn How to pronounce clozapine (audio)
: an antipsychotic drug C18H19ClN4 with serious side effects (as seizures and agranulocytosis) that is used in the management of schizophrenia

Note: Clozapine is marketed under the trademark Clozaril.

More from Merriam-Webster on clozapine

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