climbing fiber


Definition of climbing fiber


  1. :  any of the afferent nerve fibers arising from neurons in the inferior olive that ascend to the cerebellar cortex to synapse with Purkinje cells The olive sends so-called climbing fibers up to the cerebellum where they wrap around Purkinje cells like vines around a tree, exerting a powerful influence on them … — Ingrid Wickelgren, Science, 11 Sept. 1998 Individual Purkinje neurons receive synaptic input from only a single climbing fiber, whereas each climbing fiber contacts 1-10 Purkinje neurons. — Eric R. Kandel et al., Principles of Neural Science, 4th Edition, 2000

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First Known Use of climbing fiber


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to cast off or become cast off

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