citrulline

noun

cit·​rul·​line ˈsi-trə-ˌlēn 

: a crystalline amino acid C₆H₁₃N₃O₃ formed especially as an intermediate in the conversion of ornithine to arginine

Examples of citrulline in a Sentence

Recent Examples on the Web

How Watermelon Juice Affects Blood Pressure Watermelon contains l-citrulline, an amino acid that your body converts into arginine. — Lindsey Desoto, Health, 22 June 2026

Relieves Sore Muscles from Exercise Watermelon contains an amino acid called citrulline, which increases blood concentrations of L-arginine (an amino acid that helps the body build protein). — Lindsey Desoto, Rd, Ld, Verywell Health, 29 Jan. 2025

However, Red Boost also contains L-citrulline, an amino acid linked to vasodilation and blood flow. — Jon Goodwin, Discover Magazine, 30 Dec. 2022

Each scoop provides the natural benefits of creatine, caffeine, citrulline, beta-alanine, and other must-have ingredients. — The Salt Lake Tribune, 28 Oct. 2022

Word History

Etymology

International Scientific Vocabulary, from New Latin Citrullus, genus name of the watermelon

First Known Use

1930, in the meaning defined above

Rhymes for citrulline

• alkaline
• andesine
• anodyne
• anticline
• arginine
• asinine
• benzidine
• borderline
• byzantine
• calamine
• caroline
• centerline

Medical Definition

citrulline

noun

cit·​rul·​line ˈsi-trə-ˌlēn; si-ˈtrəl-ˌēn, -ən 

: a crystalline amino acid C₆H₁₃N₃O₃ formed especially as an intermediate in the conversion of ornithine to arginine in the living system