chlor·​phen·​ir·​amine ˌklȯr-(ˈ)fen-ˈir-ə-ˌmēn How to pronounce chlorpheniramine (audio)
: an antihistamine C16H19ClN2 that is usually administered in the form of its maleate

Examples of chlorpheniramine in a Sentence

Recent Examples on the Web Coricidin contains dextromethorphan and chlorpheniramine, which experts say when taken in high doses – which is typically a result of recreational use – can cause euphoria, agitation, psychoses and dissociative phenomena. Crimesider Staff, CBS News, 18 Oct. 2017 Here are six common classes of medications that Morgan can leave us feeling sluggish: Over-the-counter meds Antihistamines (e.g. Benadryl [diphenhydramine] and Chlor-Trimeton [chlorpheniramine]). Molly Kimball,, 14 June 2017

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'chlorpheniramine.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History


chlor- + phen- + -ir- (probably alteration of pyridine) + amine

First Known Use

1964, in the meaning defined above

Time Traveler
The first known use of chlorpheniramine was in 1964

Dictionary Entries Near chlorpheniramine

Cite this Entry

“Chlorpheniramine.” Dictionary, Merriam-Webster, Accessed 26 Sep. 2023.

Medical Definition


chlor·​phen·​ir·​amine -fen-ˈir-ə-ˌmēn, -mən, -fən- How to pronounce chlorpheniramine (audio)
: an antihistamine that is usually administered in the form of its maleate C16H19ClN2·C4H4O4

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