cha·​lone ˈkā-ˌlōn How to pronounce chalone (audio) ˈka- How to pronounce chalone (audio)
: a substance (such as a glycoprotein) that inhibits mitosis only in the specific tissue that secretes it compare hormone

Word History


Greek chalōn, present participle of chalan to slacken

First Known Use

1914, in the meaning defined above

Time Traveler
The first known use of chalone was in 1914

Dictionary Entries Near chalone

Cite this Entry

“Chalone.” Dictionary, Merriam-Webster, Accessed 1 Jun. 2023.

Medical Definition


: a substance (as a glycoprotein) that inhibits mitosis in the specific tissue which secretes it
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