cathepsin

play
noun ca·thep·sin \ kə-ˈthep-sən \

Definition of cathepsin

:any of several intracellular proteases of animal tissue that aid in autolysis

Origin and Etymology of cathepsin

Greek kathepsein to digest (from kata- cata- + hepsein to boil) + English 2-in


Medical Dictionary

cathepsin

play
noun ca·thep·sin \ kə-ˈthep-sən \

medical Definition of cathepsin

:any of a class of proteases present in most animal tissues (as in kidney, liver, and spleen) that catalyze the hydrolysis of proteins to polypeptides
  • Cathepsins are lysosomal proteases that cleave their substrates with relatively low specificity.
  • —Arthur M. Krieg et al.Science1 Feb. 2008
  • Recent investigations by several research groups, working with organisms as diverse as worms and monkeys, implicate cathepsins flooding the cytoplasm as a major cause of necrotic cell death.
  • —Nektarios TavernarakisNew Scientist15 Feb. 2003

catheptic

play \-tik\ adjective
    • catheptic enzymes
    • catheptic activity

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