ca·​thep·​sin | \ kə-ˈthep-sən How to pronounce cathepsin (audio) \

Definition of cathepsin

: any of several intracellular proteases of animal tissue that aid in autolysis

First Known Use of cathepsin

1929, in the meaning defined above

History and Etymology for cathepsin

Greek kathepsein to digest (from kata- cata- + hepsein to boil) + English -in entry 2

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The first known use of cathepsin was in 1929

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Cite this Entry

“Cathepsin.” Dictionary, Merriam-Webster, Accessed 17 Jan. 2021.

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ca·​thep·​sin | \ kə-ˈthep-sən How to pronounce cathepsin (audio) \

Medical Definition of cathepsin

: any of a class of proteases present in most animal tissues (as in kidney, liver, and spleen) that catalyze the hydrolysis of proteins to polypeptides Cathepsins are lysosomal proteases that cleave their substrates with relatively low specificity.— Arthur M. Krieg et al., Science, 1 Feb. 2008 Recent investigations by several research groups, working with organisms as diverse as worms and monkeys, implicate cathepsins flooding the cytoplasm as a major cause of necrotic cell death.— Nektarios Tavernarakis, New Scientist, 15 Feb. 2003

Other Words from cathepsin

catheptic \ -​tik How to pronounce cathepsin (audio) \ adjective
catheptic enzymes catheptic activity

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