carbidopa

noun

car·​bi·​do·​pa ˌkär-bə-ˈdō-pə How to pronounce carbidopa (audio)
: a drug C10H14N2O4·H2O that inhibits decarboxylation of L-dopa in tissues outside the brain and that is administered with L-dopa in the treatment of Parkinson's disease to increase the amount of L-dopa available for transport to the brain

Examples of carbidopa in a Sentence

Recent Examples on the Web However, some levodopa medications also contain carbidopa, which can counteract the interaction.4 Vitamin K and blood-thinning medications. Alyssa Hui, Verywell Health, 25 May 2023 Hinz's most controversial claim is that carbidopa — a component of the prescription Sinemet, the mainstream treatment for Parkinson's — is associated with greater death rates from the disease. Joe Carlson and Brooks Johnson, Star Tribune, 23 July 2021 Turns out that certain intestinal microbes can also digest the drug, and, surprisingly, carbidopa does not stop them. Claudia Wallis, Scientific American, 1 Jan. 2020

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'carbidopa.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History

Etymology

probably from (de)carb(oxylation) + -i- + (L-)dopa

First Known Use

1972, in the meaning defined above

Time Traveler
The first known use of carbidopa was in 1972

Dictionary Entries Near carbidopa

Cite this Entry

“Carbidopa.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/carbidopa. Accessed 20 Jul. 2024.

Medical Definition

carbidopa

noun
car·​bi·​do·​pa ˌkär-bə-ˈdō-pə How to pronounce carbidopa (audio)
: a drug C10H14N2O4·H2O that inhibits decarboxylation of L-dopa in tissues outside the brain and that is typically administered in combination with L-dopa in the treatment of Parkinson's disease to increase the amount of L-dopa available for transport to the brain

Note: Trademarks for preparations containing carbidopa include Duopa, Lodosyn, Parcopa, Rytary, Sinemet, and Stalevo.

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