: either of two tumor suppressor genes that in mutated form tend to be associated with an increased risk of certain cancers and especially breast and ovarian cancers
often used before another noun
BRCA genes
a BRCA mutation

Examples of BRCA in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Approximately 1 in 400 people carry a BRCA gene mutation. Lucy Notarantonio, MSNBC Newsweek, 3 Aug. 2025 Durand predicts that in the next decade, medical practice may move towards offering full-body imaging to more groups that are at high risk for cancer, like those with BRCA gene mutations or Lynch syndrome. Claire Bugos, Verywell Health, 18 June 2025 Anyone identified to have the BRCA mutation based on genetic testing can begin imaging even earlier—at age 25. Mara Santilli, Flow Space, 21 May 2025 For example, people with BRCA mutations may benefit from a poly(ADP)-ribose polymerase (PARP) inhibitor medication, which targets cancer’s ability to repair itself. Jamin Brahmbhatt, Verywell Health, 28 Apr. 2025 See All Example Sentences for BRCA

Word History

First Known Use

1992, in the meaning defined above

Time Traveler
The first known use of BRCA was in 1992

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Cite this Entry

“BRCA.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/BRCA. Accessed 21 Aug. 2025.

Medical Definition

: either of two tumor suppressor genes that in mutated form tend to be associated with an increased risk of certain cancers and especially breast and ovarian cancers
often used before another noun
BRCA genes
a BRCA mutation
Last Updated: - Updated example sentences
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