bio·​mark·​er | \ ˈbī-ō-ˌmär-kər How to pronounce biomarker (audio) \

Definition of biomarker

: a distinctive biological or biologically derived indicator (such as a metabolite) of a process, event, or condition (such as aging, disease, or oil formation)

Examples of biomarker in a Sentence

Recent Examples on the Web There is precedent for the FDA approving products based on a biomarker that is supposed to correlate with real-world benefit before trials are completed to prove benefit on symptoms or outcome of the disease. Caroline Chen, ProPublica, "“Fast-Tracking” a Coronavirus Vaccine Sounds Great. It’s Not That Simple.," 17 June 2020 The group also plans to support a biomarker study, followed by an early-stage clinical trial to assess whether an existing drug from Japanese pharmaceutical Daiichi Sankyo can fight PXE. Jared Whitlock, Wired, "Covid-19 Stalls Clinical Trials for Everything but Covid-19," 17 Apr. 2020 Additional data could help city access resources, testing kits Tempe and ASU have been working for nearly two years to study biomarkers in the city’s wastewater. Paulina Pineda, azcentral, "ASU researchers look for traces of COVID-19 in Tempe's sewage, which could serve as early warning system," 2 Apr. 2020 In addition to this, the team collected biomarkers from saliva and blood that could potentially help them diagnose someone with toxic stress physiology. Annabelle Timsit, Quartz, "“As important as finding the cure to cancer”: Behind the effort to end childhood toxic stress," 21 Mar. 2020 Shaked said RetiSpec is the only retinal test that doesn’t require intravenous injections or eye drops to pinpoint Alzheimer’s biomarkers., "Could a simple eye exam detect signs of Alzheimer’s disease?," 29 Oct. 2019 Others say amyloid's real importance might be as one of those biomarkers. Tanya Lewis, Scientific American, "A Harder Look at Alzheimer’s Causes and Treatments," 30 Apr. 2020 One example is the inadequacy of the PD-L1 biomarker to clearly identify responders to PD-1 blockers, a type of checkpoint inhibitor immunotherapy currently being used. Thomas Davis, STAT, "Predicting immunotherapy success: We’ve mastered the foothills but the summit lies ahead," 6 Apr. 2020 For about a year, Levine has been working with Elysium Health to create Index, an at-home test that evaluates over 100,000 epigenetic biomarkers on a person’s DNA. Nicole Saporita, Good Housekeeping, "How Old Are You Really? What New Research Says About Your Biological Age," 18 Feb. 2020

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'biomarker.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of biomarker

1973, in the meaning defined above

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The first known use of biomarker was in 1973

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Last Updated

30 Jun 2020

Cite this Entry

“Biomarker.” Dictionary, Merriam-Webster, Accessed 15 Jul. 2020.

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More Definitions for biomarker


bio·​mark·​er | \ ˈbī-ō-ˌmär-kər How to pronounce biomarker (audio) \

Medical Definition of biomarker

: a distinctive biological or biologically derived indicator (as a biochemical metabolite in the body) of a process, event, or condition (as aging, disease, or exposure to a toxic substance) age-related biomarkers of disease and degenerative change— Janet Raloff

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