bifolium

noun
bi·fo·li·um | \(ˈ)bī-ˈfō-lē-əm \
plural bifolia\(ˈ)bī-ˈfō-lē-ə \

Definition of bifolium 

: two sheets of paper, parchment, or similar material folded together to make four leaves … verses are written, not on two sheets of paper, but on the recto and verso of the first leaf of a bifolium.— Sara S. Hodson, Times Literary Supplement, 24 June 1988 Though incomplete, in its present state it occupies close to eleven hundred folios, so large that each bifolium was formed from a whole skin.— Penn R. Szittya, Speculum, April 1999

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First Known Use of bifolium

1938, in the meaning defined above

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